272105-42-7
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Basic information
- Product Name: Disitertide
- Synonyms: disitertide;L-Threonyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-L-asparagine
- CAS NO:272105-42-7
- Molecular Formula: C68H109N17O22S2
- Molecular Weight: 1580.82
- EINECS: N/A
- Product Categories: N/A
- Mol File: 272105-42-7.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 1968.718 °C at 760 mmHg
- Flash Point: 1144.439 °C
- Appearance: /
- Density: 1.327
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 3.15±0.10(Predicted)
- CAS DataBase Reference: Disitertide(CAS DataBase Reference)
- NIST Chemistry Reference: Disitertide(272105-42-7)
- EPA Substance Registry System: Disitertide(272105-42-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 272105-42-7(Hazardous Substances Data)
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272105-42-7 Usage
General Description
Disitertide is a synthetic peptide composed of 17 amino acids. It is a potent inhibitor of transforming growth factor beta (TGF-β), which is a key mediator of fibrosis and inflammation. Disitertide has been studied for its potential therapeutic effects in conditions such as pulmonary fibrosis, chronic kidney disease, and diabetic nephropathy. By blocking the actions of TGF-β, disitertide may help to reduce fibrosis and inflammation in these conditions, potentially slowing disease progression and improving outcomes for patients. Additionally, disitertide has shown promising results in preclinical studies for the treatment of other fibrotic diseases, making it a promising candidate for further development as a therapeutic agent.Check Digit Verification of cas no
The CAS Registry Mumber 272105-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,2,1,0 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.Calculate Digit Verification of CAS Registry Number 272105-42:
(8*2)+(7*7)+(6*2)+(5*1)+(4*0)+(3*5)+(2*4)+(1*2)=107
107 % 10 = 7
So 272105-42-7 is a valid CAS Registry Number.
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Disitertide
