27262-40-4 Usage
Description
(2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide is an organic compound with a specific stereochemistry and molecular structure. It is characterized by the presence of a 2S-piperidine core, a 2,6-dimethylphenyl group, and a carboxamide functional group. (2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide) is typically a white solid and is known for its potential applications in various fields due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
(2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique molecular structure allows it to serve as a building block for the development of new drugs, particularly those targeting the central nervous system.
Used in Chemical Research:
In the field of chemical research, (2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide is utilized as a research compound for studying the effects of stereochemistry on biological activity. Its specific stereochemistry can provide insights into the development of more effective and selective drugs.
Used in Anesthetic Formulation:
As a metabolite of the anesthetic Ropivacaine, (2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide may play a role in the development of new anesthetic agents or the improvement of existing ones. Its presence in the metabolism of Ropivacaine suggests potential applications in the optimization of anesthetic drugs for better efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 27262-40-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,6 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27262-40:
(7*2)+(6*7)+(5*2)+(4*6)+(3*2)+(2*4)+(1*0)=104
104 % 10 = 4
So 27262-40-4 is a valid CAS Registry Number.
27262-40-4Relevant articles and documents
A convenient and highly enantioselective synthesis of (S)-2-pipecolic acid: an efficient access to caine anesthetics
Yang, Yuyan,Li, Hua,You, Zhonglin,Zhang, Xingxian
, p. 3084 - 3089 (2021/08/12)
A novel and enantioselective synthesis of (S)-2-pipecolic acid (5) has been achieved from Oppolzer’s sultam (1) and ethyl N-(diphenylmethylene)glycinate (2) as readily available starting materials. The highly stereoselective alkylation of chiral glycine intermediate (3) with 1,4-dibromobutane afforded the key backbone of (S)-2-pipecolic acid (5) in one-step that was utilized into the preparation of the local anesthetics mepivacaine, ropivacaine and bupivacaine.
Preparation and purification method of ropivacaine hydrochloride intermediate
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Paragraph 0047; 0048; 0049; 0050; 0051; 0052; 0053-0058, (2019/04/04)
The invention relates to a preparation and purification method of a ropivacaine hydrochloride intermediate. According to the method, single chiral intermediate (-)-(2S)-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is prepared from single chiral raw mate
Preparation method of ropivacaine hydrochloride
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Paragraph 0019-0021; 0027; 0040; 0042, (2017/11/29)
The invention discloses a preparation method of ropivacaine hydrochloride. The preparation method comprises steps as follows: (1) preparation of an intermediate (I), (2) preparation of an intermediate (II), (3) preparation of a crude product and (4) refin