272788-85-9

Basic information

• Product Name: thymine-acetic acid tert-butyl ester
• Synonyms: thymine-acetic acid tert-butyl ester
• CAS NO: 272788-85-9
• Molecular Formula: C₁₁H₁₆N₂O₄
• Molecular Weight: 240
• Mol File: 272788-85-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: thymine-acetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: thymine-acetic acid tert-butyl ester(272788-85-9)
• EPA Substance Registry System: thymine-acetic acid tert-butyl ester(272788-85-9)

Safety Data

• Hazardous Substances Data: 272788-85-9(Hazardous Substances Data)

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 65-71-4 thymin 

Downstream Products

• 272788-86-0 1-tert-butoxycarbonylmethyl-O⁴-(o-nitrophenyl)thymine 
• 857636-47-6 (6-methyl-3,5-dioxo-8,8-diphenyl-7-thia-2,4-diaza-bicyclo[4.2.0]oct-2-yl)-acetic acid tert-butyl ester 
• 857636-48-7 (6-methyl-3,5-dioxo-8,8-diphenyl-7-thia-2,4-diaza-bicyclo[4.2.0]oct-2-yl)-acetic acid 
• 857636-49-8 2-(6-methyl-3,5-dioxo-8,8-diphenyl-7-thia-2,4-diaza-bicyclo[4.2.0]oct-2-yl)-N-[2-(3,7,8-trimethyl-2,4-dioxo-3,4-dihydro-2H-benzo[g]pteridin-10-yl)-ethyl]-acetamide 
• 272788-89-3 N⁴-benzoyl-1-carboxymethyl-5-methylcytosine 
• 272788-88-2 N⁴-benzoyl-1-tert-butoxycarbonylmethyl-5-methylcytosine 
• 272788-90-6 N-(2-(4-methoxyphenyl)diphenylmethylamino)ethyl-N-((N⁴-benzoyl-5-methylcytosin-1-yl)acetyl)glycine 2-cyanoethyl ester 

Relevant articles and documents

New thymine-based derivative of nitrogen mustards

This work deals with the synthesis of a new nitrogen mustard derivative based on thymine. To introduce the bis(2-chloroethyl)amine group to position 4 of the pyrimidine base, many strategies were explored and the desired compound was finally obtained, thanks to a synthetic pathway in five steps. Copyright Taylor and Francis Group, LLC.

Synthesis and hybridization properties of DNA-PNA chimeras carrying 5- bromouracil and 5-methylcytosine

The preparation of 5-bromouracil and 5-methylcytosine peptide nucleic acid (PNA) monomers is described. These PNA monomers were used for the preparation of several DNA-PNA chimeras and their hybridization properties are described. The substitution of cyto