274-67-9

Basic information

• Product Name: IMIDAZO[1,5-A]PYRIMIDINE
• Synonyms: IMIDAZO[1,5-A]PYRIMIDINE
• CAS NO: 274-67-9
• Molecular Formula: C6H5N3
• Molecular Weight: 119.12
• Mol File: 274-67-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.29
• PKA: 5.00±0.30(Predicted)
• CAS DataBase Reference: IMIDAZO[1,5-A]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: IMIDAZO[1,5-A]PYRIMIDINE(274-67-9)
• EPA Substance Registry System: IMIDAZO[1,5-A]PYRIMIDINE(274-67-9)

Safety Data

• Hazardous Substances Data: 274-67-9(Hazardous Substances Data)

Upstream product

• 542-78-9 Malondialdehyde 
• 4919-03-3 4-amino-1H-imidazole 

Downstream Products

• 106012-56-0 3-formylimidazo<1,2-a>pyrimidine 
• 273-21-2 1H-Imidazo[4,5-b]pyridine 

Relevant articles and documents

Convenient synthesis of imidazo[1,5-a]pyrimidine derivatives and their unusual recyclization into 3H-imidazo[4,5-b]pyridine derivatives

[Figure not available: see fulltext.] New derivatives of imidazo[1,5-a]pyrimidine have been synthesized by cyclization of in situ generated 1H-imidazol-4(5)-amine with 1,3-diketones or malondialdehyde derivatives. Utilization of asymmetrical 1,3-diketones leads to the formation of a mixture of regioisomers. The discovered conversion of imidazo[1,5-a]pyrimidine core into 3H-imidazo[4,5-b]pyridine that takes place only under acidic conditions can be considered as a new version of Dimroth rearrangement involving cleavage of C–N bond and formation of C–C bond.