27486-88-0 Usage
Description
TRT-CYS(TRT)-OH DEA, also known as Trt-Cys(Trt)-OH DEA, is an S-trityl protected amino acid derivative that plays a crucial role in the synthesis of specific biological molecules. Its unique structure and properties make it a valuable compound in the field of biochemistry and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
TRT-CYS(TRT)-OH DEA is used as a key intermediate for the preparation of synthetic insulin fragments. Its incorporation into the synthesis process aids in the development of insulin analogs and modified insulin molecules, which can have improved pharmacological properties and therapeutic applications in the treatment of diabetes.
Used in Biochemical Research:
In the field of biochemistry, TRT-CYS(TRT)-OH DEA serves as an essential building block for the synthesis of various peptides and proteins. Its trityl protection group helps prevent unwanted side reactions during the synthesis process, ensuring the successful assembly of the desired biologically active molecules.
Used in Drug Development:
TRT-CYS(TRT)-OH DEA is also utilized in the development of novel drugs targeting specific diseases and conditions. Its unique properties and reactivity make it a valuable component in the design and synthesis of new pharmaceutical agents, potentially leading to the discovery of more effective treatments for various health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 27486-88-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,4,8 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 27486-88:
(7*2)+(6*7)+(5*4)+(4*8)+(3*6)+(2*8)+(1*8)=150
150 % 10 = 0
So 27486-88-0 is a valid CAS Registry Number.
InChI:InChI=1/C41H35NO2S.C4H11N/c43-39(44)38(42-40(32-19-7-1-8-20-32,33-21-9-2-10-22-33)34-23-11-3-12-24-34)31-45-41(35-25-13-4-14-26-35,36-27-15-5-16-28-36)37-29-17-6-18-30-37;1-3-5-4-2/h1-30,38,42H,31H2,(H,43,44);5H,3-4H2,1-2H3
27486-88-0Relevant articles and documents
TRITYLATION REACTIONS BASED ON METALLIC CATALYSIS
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Page/Page column 29-30, (2010/11/25)
The invention relates to a method for preparing tritylated compounds in which protic functional groups are protected with the triphenylmethyl group, method based on the homogeneous catalysis exercised by salts or metal complexes in organic solvents. The invention relates in particular to a method for the selective tritylation of some groups, obtained both directly and by selective detritylation, with methods based on metallic catalysis. The application to amino acids, typical substrates not suitable to be subjected as such to homogeneous tritylations in organic solvents, indicates the ability of the method to extend also to hydrophilic substrates. The method allows to obtain with high yield pertrityl amino acids, N-tritylamino acids or amino acids tritylated only in lateral chain, compounds which heretofore were either difficult to obtain in aqueous solvents or obtainable through indirect methods. All, in any case, are important intermediates in peptide synthesis.
