27505-78-8 Usage
Description
2,3,7-Trimethylindole is an organic compound characterized by its dark purple crystalline structure. It is a derivative of indole, featuring three methyl groups at the 2nd, 3rd, and 7th positions, which contribute to its unique chemical properties and reactivity.
Uses
Used in Chemical Synthesis:
2,3,7-Trimethylindole is used as a key reactant for the synthesis and preparation of various organic compounds. Its unique structure and reactivity make it a valuable building block in the creation of a wide range of molecules with diverse applications across different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3,7-Trimethylindole is used as an intermediate in the synthesis of various drugs and drug candidates. Its ability to react with other molecules and form new compounds makes it a versatile component in the development of novel therapeutic agents.
Used in Agrochemical Industry:
2,3,7-Trimethylindole is also utilized in the agrochemical industry for the synthesis of bioactive compounds, such as pesticides and herbicides. Its unique chemical properties allow for the creation of new molecules with improved efficacy and selectivity, contributing to more effective and environmentally friendly solutions in agriculture.
Used in Dye and Pigment Industry:
Due to its dark purple color, 2,3,7-Trimethylindole can be used as a starting material for the production of dyes and pigments. Its distinctive hue can be employed in the formulation of various colorants for use in industries such as textiles, plastics, and printing.
Used in Research and Development:
2,3,7-Trimethylindole is a valuable compound for research and development purposes, particularly in the fields of organic chemistry and medicinal chemistry. Its unique structure and reactivity make it an interesting subject for studying new reaction mechanisms, exploring novel synthetic routes, and discovering new applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 27505-78-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,0 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 27505-78:
(7*2)+(6*7)+(5*5)+(4*0)+(3*5)+(2*7)+(1*8)=118
118 % 10 = 8
So 27505-78-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N/c1-7-5-4-6-10-8(2)9(3)12-11(7)10/h4-6,12H,1-3H3
27505-78-8Relevant articles and documents
Synthesis of indoles through acceptorless dehydrogenative coupling catalyzed by nickel on silica-alumina
Charvieux, Aubin,Hammoud, Abdul Aziz,Duclos, Marie-Christine,Duguet, Nicolas,Métay, Estelle
supporting information, (2021/07/25)
The high atom-economical formation of indoles from anilines and diols was described with affordable and easy to handle Ni/SiO2-Al2O3. After optimization, 2,3-dimethylindole was isolated with an excellent 98% yield in neat conditions. The scope of the reaction was studied and 13 indoles were isolated in 16–80% yields.
Fe-Catalyzed Sequential C(sp3)-H/N-H Annulation of 2-Methylindoles with Ethyl Trifluoropyruvate at Room Temperature: Construction of Pyrrolo[1,2-α]indoles
Wang, Le,Wang, Le,Zhou, Jia,Chen, Han-Qia,Li, Dong-Li,Lin, Jun-Bing,Lin, Jun-Bing,Li, Ke,Ding, Tong-Mei,Zhang, Shu-Yu,Zhang, Shu-Yu
supporting information, p. 4716 - 4720 (2020/06/29)
An efficient and benign iron-catalyzed room-temperature method was developed for direct sequential C(sp3)-H/N-H annulation to construct pyrroloindole scaffolds. This strategy features cheap and readily available raw materials and mild room-temperature reaction conditions and provides a green and practical method for the one-pot rapid synthesis of a wide range of diversely functionalized pyrrolo[1,2-α]indoles.
Stereoselective synthesis of 2,3-disubstituted indoline diastereoisomers by chemoenzymatic processes
Lopez-Iglesias, Maria,Busto, Eduardo,Gotor, Vicente,Gotor-Fernandez, Vicente
, p. 8049 - 8055,7 (2020/10/15)
Racemic indolines including a variety of structural motifs such as C-2 and C-3 substitutions (alkyl or aryl), cis/trans relative stereochemistry and functionalization of the aromatic ring (fluoro, methyl or methoxy groups) have been efficiently prepared through Fischer indolization and subsequent diastereoselective reduction of the unprotected indoles. Combination of Candida antarctica lipase type A and allyl 3-methoxyphenyl carbonate has been identified as the best tandem for their kinetic resolutions, observing excellent stereodiscriminations for most of the tested indolines.
