27561-50-8

Basic information

• Product Name: 1-bromo-2-(bromomethyl)-4-methylbenzene
• Synonyms: 1-bromo-2-(bromomethyl)-4-methylbenzene
• CAS NO: 27561-50-8
• Molecular Formula: C₈H₈Br₂
• Molecular Weight: 263.95712
• Mol File: 27561-50-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 273.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.743±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-bromo-2-(bromomethyl)-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-(bromomethyl)-4-methylbenzene(27561-50-8)
• EPA Substance Registry System: 1-bromo-2-(bromomethyl)-4-methylbenzene(27561-50-8)

Safety Data

• Hazardous Substances Data: 27561-50-8(Hazardous Substances Data)

Usage

General Description

1-bromo-2-(bromomethyl)-4-methylbenzene is a chemical compound that belongs to the class of aromatic organic compounds. It is also known as 2-bromo-1-(bromomethyl)-4-methylbenzene or dibromo-(4-methylphenyl)methane. It is composed of a benzene ring with two bromine atoms and a methyl group attached to it. 1-bromo-2-(bromomethyl)-4-methylbenzene is commonly used as an intermediate in organic synthesis and chemical research. It is also used in the production of pharmaceuticals and agrochemicals. Its properties and reactivity make it suitable for a variety of chemical reactions and applications in the industry.

Upstream product

• 583-70-0 1-bromo-2,4-dimethylbenzene 
• 75366-05-1 3-methylbicyclo<4.1.0>hepta-1,3,5-triene 
• 620-13-3 1-bromomethyl-3-methyl-benzene 
• 36583-13-8 3-methylbenzyl Co(III)(dmgH)2py 
• 7726-95-6 bromine 
• 727985-37-7 ?(2-bromo-5-methylphenyl)methanol 
• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 90971-88-3 methyl 2-bromo-5-methylbenzoate 

Downstream Products

• 1420532-42-8 2-(azidomethyl)-1-bromo-4-methyl benzene 
• 1420532-43-9 1-(2-bromo-5-methylbenzyl)-5-methyl-4-(trimethylsilyl)-1H-1,2,3-triazole 
• 1420532-44-0 1-(2-bromo-5-methylbenzyl)-5-methyl-1H-1,2,3-triazole 
• 1085539-03-2 (2-bromo-5-methylphenyl)acetonitrile 
• 203314-29-8 2-bromo-5-methylphenylacetic acid 

Relevant articles and documents

Formation of Benzo[ b ]Thiophenes by Electroreduction of Tert-Alkanecarbodithioates

The electroreduction of a 1:1-mixture of 2-bromobenzyl 2,2-dimethylpropanedithioate and 2-bromo-5-methylbenzyl 2,2-dimethylbutanedithioate led to a mixture of 2-Tert-butylbenzo[b]thiophene, 2-Tert-Amylbenzo[b]thiophene, 2-Tert-butyl-5-methylbenzo[b]thioph

tBuOK-Promoted Cyclization of Imines with Aryl Halides

A transition-metal-free indole synthesis using radical coupling of 2-halotoluenes and imines via the later-stage C-N bond construction was reported for the first time. It includes an aminyl radical generation by C-H cleaving addition of 2-halotoluenes to imines via the carbanion radical relay and an intramolecular coupling of aryl halides with aminyl radicals. One standard condition can be used for all halides including F, Cl, Br, and I. No extra oxidant or transition metal is required.

AUTOTAXIN INHIBITORS COMPRISING A HETEROAROMATIC RING-BENZYL-AMIDE-CYCLE CORE

The present invention relates to novel compounds that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in diseases and disorders mediated by autotaxin.