276257-16-0Relevant articles and documents
Design of a gag pentapeptide analogue that binds human cyclophilin a more efficiently than the entire capsid protein: New insights for the development of novel anti-HIV-1 drugs
Li, Quan,Moutiez, Mireille,Charbonnier, Jean-Baptiste,Vaudry, Karine,Ménez, André,Quéméneur, Eric,Dugave, Christophe
, p. 1770 - 1779 (2007/10/03)
Cyclophilin A (hCyp-18), a ubiquitous cytoplasmic peptidyl-prolyl cis/trans isomerase (PPIase), orchestrates HIV-1 core packaging, hCyp-18, incorporated into the virion, enables core uncoating and RNA release and consequently plays a critical role in the