27675-77-0

Basic information

• Product Name: 4-benzylactone
• Synonyms: 4-benzylactone;(-)-Parabenzlactone;(3R)-4,5-Dihydro-4β-[(R)-(1,3-benzodioxol-5-yl)hydroxymethyl]-3α-(1,3-benzodioxol-5-ylmethyl)furan-2(3H)-one;Parabenzlactone
• CAS NO: 27675-77-0
• Molecular Formula: C20H18 O7
• Molecular Weight: 370.35
• Mol File: 27675-77-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 597°Cat760mmHg
• Flash Point: 217.4°C
• Appearance: /
• Density: 1.461g/cm³
• Vapor Pressure: 4.25E-15mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 4-benzylactone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzylactone(27675-77-0)
• EPA Substance Registry System: 4-benzylactone(27675-77-0)

Safety Data

• Hazardous Substances Data: 27675-77-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H18O7/c21-19(12-2-4-16-18(7-12)27-10-25-16)14-8-23-20(22)13(14)5-11-1-3-15-17(6-11)26-9-24-15/h1-4,6-7,13-14,19,21H,5,8-10H2/t13-,14+,19+/m1/s1

Upstream product

• 17680-04-5 (3,4-methylenedioxy)phenylmagnesium bromide 
• 96249-87-5 (E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride 
• 307500-29-4 2-propenyl (Z,E)-3-(1,3-benzodioxol-5-yl)-N-methoxy-2-propenimidate 
• 307500-27-2 (E)-3-(1,3-benzodioxol-5-yl)-N-methoxy-2-propenamide 
• 139219-22-0 2,3-trans-(α-benzyloxy-3,4-methylenedioxybenzyl)-2-(3,4-methylenedioxybenzyl)butan-4-olide 
• 80483-34-7 4-(1,3-benzodioxol-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one 
• 2606-51-1 3,4-Methylenedioxybenzyl bromide 
• 16167-44-5 3-(1-(hydroxy)-1-(3,4-methylenedioxyphenyl)methyl)-4-butanolide 
• 96960-95-1 3-(α-bromo-3,4-methylenedioxybenzyl)butan-4-olide 
• 139219-15-1 3-(α-benzyloxy-3,4-methylenedioxybenzyl)butan-4-olide 
• 27675-79-2 (3R,4R)-4-(Benzo<1,3>dioxol-5-carbonyl)-3-(benzo<1,3>dioxol-5-yl)methyl-4,5-dihydrofuran-2(3H)-one 
• 877438-74-9 (8R,8'R)-4,4',5,5'-bis(methylenedioxy)-7'-(propane-1,3-diyldithio)lignano-9,9'-lactone 
• 56579-86-3 2-(3,4-methylenedioxyphenyl)-1,3-dithiane 
• 136031-30-6 (3R)-3-[(propane-1,3-diyldithio)-(3,4-methylenedioxyphenyl)methyl]butano-4-lactone 

Relevant articles and documents

Asymmetric synthesis, stereochemistry and rearrangement reactions of naturally occurring 7′-hydroxylignano-9,9′-lactones

The asymmetric synthesis of a series of (7′S,8R,8′R)-7′- hydroxylignano-9,9′-lactones is presented, among them the mammalian lignan (7′S)-hydroxyenterolactone and (7′S)-parabenzlactone, allowing the stereochemistry of natural occurring (-)-parabenzlactone

Hydroximate as a synthetically useful functional group part II: Synthesis of (±)-oxo-parabenzlactone

A stereoselective route to (±)-oxo-parabenzlactone has been developed by the combination of thiyl radical addition-cyclization of dienylhydroximate and subsequent conversion of the resulting cyclic hydroximate to lactone.