27699-67-8Relevant articles and documents
An anionic nucleophilic catalyst system for the diastereoselective synthesis of trans-β-lactams
Weatherwax, Anthony,Abraham, Ciby J.,Lectka, Thomas
, p. 3461 - 3463 (2005)
(Chemical Equation Presented) Trans-disubstituted β-lactams show increasing utility and prominence in numerous pharmaceutical applications, making their asymmetric synthesis an attractive goal for chemists. We introduce an anionic, nucleophilic catalyst s
A Domino Route toward Polysubstituted Pyrroles from 2-Imidazolines and Electron-Deficient Alkynes
Festa, Alexey A.,Golantsov, Nikita E.,Golubenkova, Alexandra S.,Varlamov, Alexey V.,Voskressensky, Leonid G.
supporting information, (2020/06/29)
The reaction of 1,2-disubstituted 2-imidazolines with electron-deficient alkynes proceeds as a pseudo-three-component process and forms imidazolidines with an N-vinylpropargylamine fragment. Heating the resulting imidazolidines in xylene on air leads to a
Palladium-catalyzed multicomponent synthesis of 2-aryl-2-imidazolines from aryl halides and diamines
Geden, Joanna V.,Pancholi, Alpa K.,Shipman, Michael
, p. 4158 - 4164 (2013/05/22)
An efficient palladium-catalyzed three-component reaction that combines aryl halides, isocyanides, and diamines provides access to 2-aryl-2-imidazolines in yields up to 96%. Through variation of the diamine component, the reaction can be extended to the s
