277756-46-4 Usage
Description
1-TRIFLUOROMETHYLCYCLOPROPANE-1-CARBOXYLIC ACID is an organic compound characterized by its solid state and a unique chemical structure that features a cyclopropane ring with a trifluoromethyl group and a carboxylic acid functional group. This molecule serves as a crucial intermediate in the synthesis of specific pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
1-TRIFLUOROMETHYLCYCLOPROPANE-1-CARBOXYLIC ACID is used as a key intermediate in the synthesis of MK-5046, a potent and selective bombesin receptor subtype-3 agonist. The application reason for this use is to facilitate the development of novel treatments for obesity by targeting the specific receptor, potentially leading to more effective therapies.
Additionally, while not explicitly mentioned in the provided materials, due to its unique chemical structure and reactivity, 1-TRIFLUOROMETHYLCYCLOPROPANE-1-CARBOXYLIC ACID may also have potential applications in other areas of the chemical and pharmaceutical industries, such as the synthesis of other bioactive compounds or materials with specific properties. However, further research and development would be necessary to explore and validate these potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 277756-46-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,7,7,5 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 277756-46:
(8*2)+(7*7)+(6*7)+(5*7)+(4*5)+(3*6)+(2*4)+(1*6)=194
194 % 10 = 4
So 277756-46-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H5F3O2/c6-5(7,8)4(1-2-4)3(9)10/h1-2H2,(H,9,10)
277756-46-4Relevant articles and documents
Preparation method and intermediate of 1-(-trifluoromethyl) cyclopropane -1- carboxylic acid compound (by machine translation)
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Paragraph 0092-0094; 0095; 0097; 0101, (2020/03/17)
The invention relates to a preparation method 1 - (of) trifluoromethyl I cyclopropane - 1 1-carboxylic acid type, compound, which is a novel, effective and safe and environment-friendly preparation method. of 1 - (-trifluoromethyl) cyclopropane - 1 1-carboxylic acid as a medicine intermediate body for preparing a final drug. (by machine translation)
Preparation method of trifluoromethyl substituted carboxylic acid compound
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Paragraph 0100; 0101, (2019/01/23)
The invention provides a preparation method of a trifluoromethyl substituted carboxylic acid compound. The method is significantly advantageous over processes in the prior art. Advantages are reflected in low cost and high yield. Another alternative schem