278169-72-5Relevant articles and documents
A new roate to cationic half-sandwich ruthenium(II) complexes with chiral cyclopentadienylphosphane ligands
Doppiu, Angelino,Salzer, Albrecht
, p. 2244 - 2252 (2004)
Optically active cyclopentadieny-linked phosphane ligands Ln of general formula C5H5CH2CH(R) PR′2 (R = Ph, R′ = Ph, L1; R = Ph, R′ = Cy, L2; R = mesityl, R′ = Ph, L3)
Stereospecific copper(II)-catalyzed tandem ring opening/oxidative alkylation of donor-acceptor cyclopropanes with hydrazones: Synthesis of tetrahydropyridazines
Mishra, Manmath,De, Pinaki Bhusan,Pradhan, Sourav,Punniyamurthy, Tharmalingam
, p. 10901 - 10910 (2019/09/13)
Aerobic copper(II)-catalyzed tandem ring opening and oxidative C-H alkylation of donor-acceptor cyclopropanes with bisaryl hydrazones is accomplished to produce tetrahydropyridazines, in which copper(II) plays dual role as a Lewis acid as well as redox catalyst. The reaction is stereospecific, and optically active cyclopropanes can be reacted with high optical purities (89-98% enantiomeric excess). The substrate scope, functional group tolerance, dual role of the copper(II) catalyst, and the use of air as an oxidant are the important practical features. A product bearing a 3-bromoaryl group can be subjected to Pd-catalyzed Suzuki coupling with boronic acid in high yield.