27848-80-2 Usage
Description
L-Lactic Acid Lithium Salt is a white fine crystalline powder that serves as a useful chiral synthon and building block for depsipeptides.
Uses
Used in Pharmaceutical Industry:
L-Lactic Acid Lithium Salt is used as a chiral synthon for the synthesis of various pharmaceutical compounds, providing a key building block for the development of new drugs with improved efficacy and selectivity.
Used in Peptide Synthesis:
L-Lactic Acid Lithium Salt is used as a building block for the synthesis of depsipeptides, which are a class of peptides containing both amide and ester linkages. These depsipeptides have potential applications in various fields, including medicine, agriculture, and materials science, due to their unique properties and diverse biological activities.
Biochem/physiol Actions
L-lactate is produced from pyruvate by the enzyme Lacate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells.
Check Digit Verification of cas no
The CAS Registry Mumber 27848-80-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,8,4 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27848-80:
(7*2)+(6*7)+(5*8)+(4*4)+(3*8)+(2*8)+(1*0)=152
152 % 10 = 2
So 27848-80-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H6O3.Li/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1
27848-80-2Relevant articles and documents
Complete conversion of l-lactate into d-lactate. A generic approach involving enzymatic catalysis, electrochemical oxidation of NADH, and electrochemical reduction of pyruvate
Biade, Azz-Eddine,Bourdillon, Christian,Laval, Jean-Marc,Mairesse, Gilles,Moiroux, Jacques
, p. 893 - 897 (2007/10/02)
L-Lactate was converted into D-lactate with a yield better than 97%, the system involving stereospecific catalysis of L-lactate oxidation by the rather cheap L-lactate dehydrogenase plus electrochemical regeneration of NAD+ at the anode and electrochemical reduction of pyruvate at the cathode. Such an approach can be extended to mere deracemization or complete inversion of all types of chiral α-alcohol-acids provided that the dehydrogenase related to the isomer to be inverted is available. Efficiency was not limited by enzyme or coenzyme deactivations.
