278605-39-3

Basic information

• Product Name: (2R,4S,5R)-2-[(1S)-α-Fluorobenzyl]-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine
• CAS NO: 278605-39-3
• Molecular Weight: 319.316
• Mol File: 278605-39-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,4S,5R)-2-[(1S)-α-Fluorobenzyl]-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4S,5R)-2-[(1S)-α-Fluorobenzyl]-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine(278605-39-3)
• EPA Substance Registry System: (2R,4S,5R)-2-[(1S)-α-Fluorobenzyl]-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine(278605-39-3)

Safety Data

• Hazardous Substances Data: 278605-39-3(Hazardous Substances Data)

Upstream product

• 18406-56-9 Bis(trimethylsilyl) benzylphosphonate 
• 1499-19-0 benzylphosphonic dichloride 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 6881-57-8 benzylphosphonic acid 
• 278605-33-7 (2R,4S,5R)-2-benzyl-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine 

Relevant articles and documents

Preparation of chiral α-monofluoroalkylphosphonic acids and their evaluation as inhibitors of protein tyrosine phosphatase 1B

Enantiomerically pure α-monofluoroalkylphosphonic acids 4-9 were synthesized by diastereoselective electrophilic fluorination of α-carbanions of asymmetric phosphonamidates bearing (-)-ephedrine as a chiral auxiliary. The diastereomeric excess of the fluo