28000-66-0

Basic information

• Product Name: Phenol, 2,6-bis(1-methylethyl)-, acetate
• CAS NO: 28000-66-0
• Molecular Formula: C14H20O2
• Molecular Weight: 220.312
• Mol File: 28000-66-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phenol, 2,6-bis(1-methylethyl)-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,6-bis(1-methylethyl)-, acetate(28000-66-0)
• EPA Substance Registry System: Phenol, 2,6-bis(1-methylethyl)-, acetate(28000-66-0)

Safety Data

• Hazardous Substances Data: 28000-66-0(Hazardous Substances Data)

Upstream product

• 108-22-5 Isopropenyl acetate 
• 2078-54-8 2,6-diisopropylphenol 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 463-51-4 Ketene 

Downstream Products

• 467213-73-6 dicyclohexylboranyl-acetic acid 2,6-diisopropyl-phenyl ester 
• 720-19-4 3',5'-diisopropyl-4'-hydroxyacetophenone 

Relevant articles and documents

O-acylation of substituted phenols with various alkanoyl chlorides under phase-transfer catalyst conditions

Esterification of several types of mono-and disubstituted phenols with various mono-and dialkanoyl chlorides was performed in phase-transfer catalysis conditions, using tetrabutylammonium chloride in a mixture of aqueous NaOH and dichloromethane. The process is particularly efficient (almost quantitative yields) as well as rapid (only 5 min reaction time, at a temperature of0°C). Taylor & Francis Group, LLC.

Derivatives of heterocycles with 5 members, their preparation and their use as medicaments

The invention relates to thiazole, oxazole, imidazole, isoxazole and isoxazoline derivatives of general formula (I) wherein Het is thiazole, oxazole, imidazole, isoxazole or isoxazoline, n is an integer from 0 to 6, A is notably selected from various optionally substituted aromatic radicals, B is notably hydrogen, alkyl or phenyl, R1 and R2 are notably independently hydrogen, alkyl or cycloalkyl and Ω is —NR46R47 or —OR48 R46 and R47 are notably independently hydrogen, alkyl, cycloalkyl or —(CH2)k—COOR51, R51 is notably alkyl or haloalkyl and R48 is notably hydrogen or alkyl. These compounds have advantageous pharmacological properties which allow their use in therapeutics, notably for treating neurodegenerative disorders or pain.

Pharmaceutically active bicyclic-heterocyclic amines

The pharmaceutically active bicyclic heterocyclic amines (XXX) STR1 where W1 is --N= or --CH=; W3 is --N= or --CH=; W5 is --N= or --CR5 -- with the proviso that W5 is --CR5 -- when both W1 and W3 are --N= which are useful as pharmaceuticals in treating mild and/or moderate to severe head injury, subarachnoid hemorrhage and subsequent ischemic stroke, asthma and reduction of mucous formation/secretion in the lung and other diseases and injuries.