28010-27-7

Basic information

• Product Name: Propanedioic acid, [(2E)-1-methyl-3-phenyl-2-propenylidene]-
• CAS NO: 28010-27-7
• Molecular Formula: C13H12O4
• Molecular Weight: 232.236
• Mol File: 28010-27-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(2E)-1-methyl-3-phenyl-2-propenylidene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(2E)-1-methyl-3-phenyl-2-propenylidene]-(28010-27-7)
• EPA Substance Registry System: Propanedioic acid, [(2E)-1-methyl-3-phenyl-2-propenylidene]-(28010-27-7)

Safety Data

• Hazardous Substances Data: 28010-27-7(Hazardous Substances Data)

Upstream product

• 22035-53-6 dimethyl isopropylidenemalonate 
• 100-52-7 benzaldehyde 

Downstream Products

• 20430-09-5 (2Z,4E)-3-methyl-5-phenylpenta-2,4-dienoic acid 
• 29643-79-6 4-methyl-6-phenyl-5,6-dihydro-2H-pyran-2-one 
• 68036-69-1 (E)-2-methyl-4-phenyl-1,3-butadiene 
• 20430-13-1 (2E,4E)-3-methyl-5-phenyl-2,4-pentadienoic acid 
• 340167-06-8 4-methyl-2-oxo-6-phenyl-5,6-dihydro-2H-pyran-3-carboxylic acid 

Relevant articles and documents

A tentative descriptive modelling of chemical structure-biological activity relationships. Biological evaluation of a series of polyethylenic acids

48 new polyethylenic-malonic acids have been submitted to an antimicrobial and antifungal screening. After a suitable recoding, the experimental results were analyzed according to two mathematical multivariate analysis using a computer process i.e. Correspondence Factorial Analysis and Cluster Analysis. These methods allowed an accurate study of the structure of the system and a thorough investigation of the structure-activity-specificity relationships. On the other side, magnitude and/or specificity of the observed biological effects were related to structural features. These results should be useful in order to elaborate synthetic strategies.