28163-88-4Relevant articles and documents
Switchable Site-Selective Catalytic Carboxylation of Allylic Alcohols with CO2
van Gemmeren, Manuel,B?rjesson, Marino,Tortajada, Andreu,Sun, Shang-Zheng,Okura, Keisho,Martin, Ruben
supporting information, p. 6558 - 6562 (2017/05/29)
A switchable site-selective catalytic carboxylation of allylic alcohols has been developed in which CO2 is used with dual roles, both facilitating C?OH cleavage and as a C1 source. This protocol is characterized by its mild reaction conditions, absence of stoichiometric amounts of organometallic reagents, broad scope, and exquisite regiodivergency which can be modulated by the type of ligand employed.
(E)-beta,gamma-alkenyl carboxylic acid derivative and preparation method thereof
-
Paragraph 0083-0086, (2017/08/31)
The invention discloses an (E)-beta,gamma-alkenyl carboxylic acid derivative and a preparation method thereof. The preparation method disclosed by the invention comprises the following steps: in an organic solvent, under the condition that a nickel catalyst, a dinitrogen ligand, a reducer and an additive exist, carrying out a carboxylation reaction on an allyl alcohol substrate as shown in formula (II) and carbon dioxide. The preparation method disclosed by the invention is high in selectivity, the raw material reagents are easy to get and has high chemical selectivity and region selectivity, and the derivative is high in yield, high in purity, and low in generation cost and is more applicable for industrial production. (Refer to Specification).
A 3 - methylthio - γ - method for preparing lactone (by machine translation)
-
Paragraph 0012; 0013, (2017/04/12)
The invention relates to shown in the following formula of 3 - methylthio - γ - method for preparing lactone: The method comprises the steps: aliphatic aldehyde with malonic acid in dimethyl sulfoxide in acetic acid piperidine salt under the catalytic action of the 100 °C the left and the right reaction, to obtain (E)- 3 - alkane olefine acid, yield 55 - 85%; in the - 78 - 10 °C will b a asian sulphone drop added to the oxalyl chloride in dichloromethane solution, then the (E)- 3 - alkane olefine acid added, at - 78 - 30 °C reaction, to obtain 3 - methylthio - γ - lactone, yield 60 - 82%. (by machine translation)