28200-63-7 Usage
Description
3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazol-8-ol is an alkaloid found in the leaves of Murraya koenigii Spreng. 3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazol-8-ol forms colorless crystals from ethanol and contains one hydroxyl group and three methyl groups, with two of the methyl groups being geminal dimethyls.
Uses
Used in Pharmaceutical Industry:
3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazol-8-ol is used as a pharmaceutical compound for its potential therapeutic properties. The presence of the hydroxyl and methyl groups in its structure allows for interactions with various biological targets, making it a promising candidate for the development of new drugs.
Used in Chemical Research:
This alkaloid is also used in chemical research for studying its structural properties and potential applications in the synthesis of other compounds. The unique arrangement of the hydroxyl and methyl groups in its structure can provide insights into the development of novel chemical reactions and methodologies.
Used in Natural Product Chemistry:
3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazol-8-ol is used in the field of natural product chemistry for understanding its role in the plant Murraya koenigii Spreng. and its potential biological activities. This can lead to the discovery of new bioactive compounds and their applications in various industries, such as agriculture, cosmetics, and pharmaceuticals.
References
Kureel et at., Chem. & Ind., 1262 (I970)
Narasimhan et at., Ind. J. Chem., 8,473 (1970)
Check Digit Verification of cas no
The CAS Registry Mumber 28200-63-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,0 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 28200-63:
(7*2)+(6*8)+(5*2)+(4*0)+(3*0)+(2*6)+(1*3)=87
87 % 10 = 7
So 28200-63-7 is a valid CAS Registry Number.
28200-63-7Relevant articles and documents
Synthesis of the Pyrano[3,2- a ]carbazole Alkaloids Koenine, Koenimbine, Koenigine, Koenigicine, and Structural Reassignment of Mukonicine
Schuster, Christian,R?nnefahrt, Marika,Julich-Gruner, Konstanze K.,J?ger, Anne,Schmidt, Arndt W.,Kn?lker, Hans-Joachim
, p. 150 - 160 (2015/12/26)
Using the palladium(II)-catalyzed oxidative cyclization of a diarylamine and the annulation of a dimethylpyran ring by Lewis acid promoted reaction with prenal as key steps, the total syntheses of the 6-oxygenated pyrano[3,2-a]carbazole alkaloids koenine and koenimbine, and of the 6,7-dioxygenated pyrano[3,2-a]carbazole alkaloids koenigine and koenigicine (koenimbidine, koenidine) were achieved. Moreover, these studies led to an improved synthetic route to the 2,6-dioxygenated carbazole alkaloid glycozolidol. Mukonicine, originally published as 6,8-dimethoxypyrano[3,2-a]carbazole, was found to be identical with koenigicine.
