2834-05-1 Usage
Description
11-Bromoundecanoic acid is a bromo-modified undecanoic acid derivative, characterized by its faintly beige crystalline solid appearance. It is known for its reactivity, particularly in the synthesis of various compounds such as 11-phenoxyundecyl phosphate and 11-hydroxytetradecanoic acid. Additionally, it has been utilized as a reactant for the preparation of hydroxy-substituted naphthoquinone cations, which are recognized for their antiplasmodial properties.
Uses
Used in Pharmaceutical Industry:
11-Bromoundecanoic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its application is primarily due to its reactivity and ability to form new compounds with potential therapeutic uses.
Used in Chemical Synthesis:
In the field of chemical synthesis, 11-Bromoundecanoic acid is used as a reactant for creating new chemical entities. Its role is crucial in the production of 11-phenoxyundecyl phosphate and 11-hydroxytetradecanoic acid, which may have specific applications in various industries.
Used in Antimalarial Drug Development:
11-Bromoundecanoic acid is used as a reactant in the preparation of hydroxy-substituted naphthoquinone cations, which are known to possess antiplasmodial properties. This application is significant in the ongoing efforts to develop new and effective antimalarial drugs.
Used in Organic Chemistry Research:
As a bromo-modified undecanoic acid derivative, 11-Bromoundecanoic acid is also utilized in organic chemistry research. It serves as a valuable compound for understanding the properties and behavior of similar molecules, contributing to the broader knowledge base in the field.
References
Navarro, I, G. Fabriás, and F. Camps. "Synthesis of [14, 14, 14-2H3] 12-hydroxytetradecanoic acid and [13,14-2H2] 11-hydroxytetradecanoic acid useful as tracers to study a (11E)-desaturation reaction in Spodoptera littoralis." Bioorganic & Medicinal Chemistry 4.3(1996):439-443.
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Check Digit Verification of cas no
The CAS Registry Mumber 2834-05-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,3 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2834-05:
(6*2)+(5*8)+(4*3)+(3*4)+(2*0)+(1*5)=81
81 % 10 = 1
So 2834-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H21BrO2/c12-10-8-6-4-2-1-3-5-7-9-11(13)14/h1-10H2,(H,13,14)/p-1
2834-05-1Relevant articles and documents
Howeel,Pattison
, p. 949 (1955)
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Raasch
, p. 2956,2959 (1953)
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Method for preparing 12-aminododecanoic acid
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Paragraph 0015; 0016, (2018/04/01)
The invention relates to a method for preparing 12-aminododecanoic acid and belongs to the technical field of synthesis of long carbon chain nylon monomers. The method comprises the following steps: carrying out a substitution reaction on 10-undecenoic acid and hydrogen bromide to produce 11-bromo-undecanoic acid; carrying out a hydrocyanation reaction with a cyanide reagent K[Fe(CN)6].3H2O to produce 11-cyan-undecanoic acid; and carrying out a reduction reaction, thereby obtaining the final product 12-aminododecanoic acid. The method disclosed by the invention has the advantages of being short in synthetic route, low in cost, flexible in operation, high in reaction yield, capable of obtaining the high-purity product and the like, and is very suitable for small-dose large-scale production of pharmaceutical companies or labs.
A -10 preparation of cavity 11-amino undecanoic acid method
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Paragraph 0031, (2017/02/09)
The invention relates to a process for producing nylon 11 resin by utilizing castor oil, in particular to a method for preparing 11-aminoundecanoic acid by utilizing 10-undecenoic acid. The method comprises the following steps: proportioning 10-undecenoic acid, methylbenzene and benzene to prepare a raw material solution, and generating 11-bromoundecanoic acid by virtue of the additive reaction of the raw material solution with hydrogen bromide in a double-kettle reaction device in the presence of catalyst; ammonolyzing the 11-bromoundecanoic acid by virtue of three different processing ways without the crystallization; adding a phase-transfer catalyst in the ammonolysis reaction to accelerate the ammonolysis reaction; carrying out vacuum filtering after the ammonolysis reaction is completed, wherein a filter cake is a 11-aminoundecanoic acid crude product; adding the crude product into the deionized water, dissolving the crude product by heating the crude product, cooling and crystallizing the crude product, and filtering the crude product to obtain the refined 11-aminoundecanoic acid product.
