28771-65-5

Basic information

• Product Name: 6-methyl-6-phenyltetrahydro-2H-pyran-2-one
• Synonyms: 6-methyl-6-phenyltetrahydro-2H-pyran-2-one
• CAS NO: 28771-65-5
• Molecular Weight: 190.242
• Mol File: 28771-65-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 6-methyl-6-phenyltetrahydro-2H-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-6-phenyltetrahydro-2H-pyran-2-one(28771-65-5)
• EPA Substance Registry System: 6-methyl-6-phenyltetrahydro-2H-pyran-2-one(28771-65-5)

Safety Data

• Hazardous Substances Data: 28771-65-5(Hazardous Substances Data)

Upstream product

• 174708-24-8 5-phenyl-5-pentenoic acid 
• 132179-72-7 (E)-5-phenylhex-4-enoic acid 
• 765-43-5 Cyclopropyl methyl ketone 
• 100-58-3 phenylmagnesium bromide 
• 3574-91-2 BrCH₂CH₂CH=C(Ph)CH₃ 
• 21865-76-9 4-phenylpentane-1,4-diol 
• 98-86-2 acetophenone 
• 24175-21-1 5-[1,3]dioxolan-2-yl-2-phenyl-pentan-2-ol 
• 3128-06-1 5-ketohexanoic acid 
• 4743-74-2 2-phenylpent-4-en-2-ol 
• 201230-82-2 carbon monoxide 
• 133549-38-9 2-methyl-2-phenyltetrahydrofuran-6-ol 
• 13984-50-4 methyl levulinate 
• 1029-55-6 5-oxo-hexanoic acid-((1R)-menthyl ester) 

Relevant articles and documents

ZnI2/Zn(OTf)2-TsOH: A versatile combined-Acid system for catalytic intramolecular hydrofunctionalization and polyene cyclization

A mild and efficient combined-Acid system using a zinc(ii) salt [ZnI2 or Zn(OTf)2] and p-Toluene sulfonic acid (TsOH) was investigated for catalytic cationic cyclizations, including intramolecular hydrocarboxylation, hydroalkoxylation, hydroamination, hydroamidation, hydroarylation and polyene cyclizations. This reaction provides easy access to five-and six-membered O-and N-containing saturated heterocyclic compounds, tetrahydronaphthalene derivatives and polycyclic skeletons in excellent yield with perfect Markovnikov selectivity and under mild conditions. The operational simplicity, broad applicability, and use of inexpensive commercially available catalysts make this protocol superior to existing methodologies.

Asymmetric bromolactonization catalyzed by a C3-symmetric chiral trisimidazoline

A productive alliance: In an enantioselective organocatalytic bromolactonization of 5-substituted hex-5-enoic acids (see scheme), it appears that the formation of an ion pair through interaction of the trisimidazoline catalyst 1 with the substrate both cr

A new synthesis of lactones from tertiary alkenylcarbinols by cobalt-catalyzed photocarbonylation under ambient conditions

In the presence of a Co catalyst, tertiary vinyl-, propenyl-, and allylcarbinols were chelatively cycloadded to carbon monoxide to produce lactones by xanthone-sensitized photoreaction in tetrahydrofuran, under CO at 1 atmosphere and at room temperature.At lower temperatures the isomerization of alkenyl-carbinols was suppressed and lactones were obtained with improved selectivity.The photoprocess was facilitated by addition of pyridine or hydrogen and retarded in presence of amines or phosphines.Mechanistic interpretations for the process and the accompanying effects are discussed.Key words: chelative carbonylation, photocarbonylation, carbonylation of olefins, lactones synthesis from alkenylalcohols.