28823-18-9

Basic information

• Product Name: Benzenesulfonothioic acid, 4-methyl-, S-(4-chlorophenyl) ester
• CAS NO: 28823-18-9
• Molecular Formula: C13H11ClO2S2
• Molecular Weight: 298.814
• Mol File: 28823-18-9.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Benzenesulfonothioic acid, 4-methyl-, S-(4-chlorophenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonothioic acid, 4-methyl-, S-(4-chlorophenyl) ester(28823-18-9)
• EPA Substance Registry System: Benzenesulfonothioic acid, 4-methyl-, S-(4-chlorophenyl) ester(28823-18-9)

Safety Data

• Hazardous Substances Data: 28823-18-9(Hazardous Substances Data)

Upstream product

• 536-57-2 p-toluene sulfinic acid 
• 106-54-7 p-Chlorothiophenol 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 65264-00-8 4-chloromophenyl 4'-methylphenyl disulfide 
• 459-44-9 4-methylbenzenediazonium tetrafluoroborate 
• 1593-60-8 p-toluenesulfonylhydroxylamine 
• 28519-50-8 potassium thiotosylate 
• 3753-27-3 sodium 4-methylbenzenesulfonothioate 
• 106-49-0 p-toluidine 
• 2943-42-2 di(4-methyl)phenylthiosulfonate 
• 42839-20-3 1-((4-chlorophenyl)thio)pyrrolidine-2,5-dione 
• 34220-01-4 di-(4-chlorophenyl)iodonium chloride 

Downstream Products

• 13343-26-5 phenyl p-chlorophenyl sulfide 
• 39248-93-6 4-methyl(thiobenzoic) acid S-(4-chlorophenyl) ester 
• 28047-22-5 1-((4-chlorophenyl)thio)piperidine 
• 536-57-2 p-toluene sulfinic acid 
• 53603-22-8 3-p-Chlorophenylthio-4-hydroxy-6-methyl-2-pyrone 

Relevant articles and documents

Electrochemical cross-coupling reactions of sodium arenesulfinates with thiophenols and phenols

A green electrochemical oxidative cross-coupling protocol for the generation of thiosulfonates and sulfonate esters using sodium arenesulfinates and thiophenols/phenols is disclosed. The protocol involves using inorganic and non-toxic NaI as both redox catalyst and supporting electrolyte at room temperature without oxidant and base. The reactions provide good yields of products and tolerate broad substrate scope. The mechanistic studies revealed that the reactions proceed via a radical pathway for the formation of SO2–S and SO2–O bonds.

Atom transfer radical addition to styrenes with thiosulfonates enabled by synergetic copper/photoredox catalysis

A synergetic copper/photoredox catalyzed ATRA of styrenes and thiosulfonates is developed. Besides aryl ethylenes, the challenging α-substituted styrenes were employed to construct the benzylic quaternary carbon centers. Owing to the mild conditions as well as the high level of substrate compability, this ATRA could be applied to derivatize bioactive natural products in late stage, and to install fluorophores across alkenes. The mechanistic studies reveal sulfonyl radicals as the key intermediate in the transformation.

TFA promoted multi-component reaction of aryldiazonium with sodium metabisulphite and thiols: Construction of thiosulfonate under transition-metal free conditions

A TFA promoted multi-component reaction of aryldiazonium with sodium metabisulphite and thiols to construct thiosulfonates under transition-metal free conditions is reported. The thiosulfonates were isolated in good yields with broad tolerance of function