2905-68-2Relevant articles and documents
Rational principles for modulating fluorescence properties of fluorescein
Ueno, Tasuku,Urano, Yasuteru,Setsukinai, Ken-Ichi,Takakusa, Hideo,Kojima, Hirotatsu,Kikuchi, Kazuya,Ohkubo, Kei,Fukuzumi, Shunichi,Nagano, Tetsuo
, p. 14079 - 14085 (2004)
Rational design strategies based on practical fluorescence modulation mechanisms would enable us to rapidly develop novel fluorescence probes for target molecules. Here, we present a practical and general principle for modulating the fluorescence properti
Site-Selective Cross-Coupling of Remote Chlorides Enabled by Electrostatically Directed Palladium Catalysis
Golding, William A.,Pearce-Higgins, Robert,Phipps, Robert J.
supporting information, p. 13570 - 13574 (2018/10/20)
Control of site-selectivity in chemical reactions that occur remote from existing functionality remains a major challenge in synthetic chemistry. We describe a strategy that enables three of the most commonly used cross-coupling processes to occur with high site-selectivity on dichloroarenes that bear acidic functional groups. We have achieved this by repurposing an established sulfonylated phosphine ligand to exploit its inherent bifunctionality. Mechanistic studies suggest that the sulfonate group engages in attractive electrostatic interactions with the cation associated with the deprotonated substrate, guiding cross-coupling to the chloride at the arene meta position. This counterintuitive combination of anionic ligand and anionic substrate demonstrates an alternative design principle when considering the application of noncovalent interactions to direct catalysis.
Azabicyalo derivative as well as preparation and application thereof
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Paragraph 0203; 0204, (2016/10/07)
The invention relates to an azabicyalo derivative as well as preparation and application thereof, and particularly discloses a compound with a structure shown in to the formula (A) or salt thereof acceptable in agricultural pharmacology. The compound in the formula (A) is described in the description in detail, and has an excellent killing effect on nematode.