29110-74-5 Usage
Description
3-Chloro-1H-Indazole is an indazole derivative featuring an electron-withdrawing chlorine atom at the 3-position. It is characterized by its almost white to light beige fluffy powder appearance and is known for its unique chemical properties that make it a versatile compound in various applications.
Uses
Used in Pharmaceutical Industry:
3-Chloro-1H-Indazole is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its electron-withdrawing nature and structural features contribute to its utility in the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 3-Chloro-1H-Indazole serves as a valuable building block for the creation of novel indazole-based molecules. Its reactivity and structural properties make it an attractive candidate for further exploration and modification in the pursuit of new chemical entities with specific biological activities.
Used in the Preparation of 3-Chloro-1-(4′-Methylphenyl)-Indazole:
Specifically, 3-Chloro-1H-Indazole has been utilized in the preparation of 3-chloro-1-(4′-methylphenyl)-indazole, which is an important compound in its own right. This derivative may have potential applications in various fields, such as pharmaceuticals, materials science, or chemical research, depending on its properties and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 29110-74-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,1,1 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 29110-74:
(7*2)+(6*9)+(5*1)+(4*1)+(3*0)+(2*7)+(1*4)=95
95 % 10 = 5
So 29110-74-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClN2/c8-7-5-3-1-2-4-6(5)9-10-7/h1-4H,(H,9,10)
29110-74-5Relevant articles and documents
Decarboxylative Bromination of Heteroarenes: Initial Mechanistic Insights
Patel, Pritesh R.,Henderson, Scott H.,Roe, Mark S.,Honey, Mark A.
supporting information, p. 1603 - 1607 (2020/09/09)
After an initial report from our laboratory describing metal-free decarboxylative halogenation of various azaheteroarenes, we set out to investigate the possible mechanism by which this chemistry occurs. Evidence from this mechanistic investigation sugges
Visible-light photocatalytic activation of N-chlorosuccinimide by organic dyes for the chlorination of arenes and heteroarenes
Rogers, David A.,Gallegos, Jillian M.,Hopkins, Megan D.,Lignieres, Austin A.,Pitzel, Amy K.,Lamar, Angus A.
, (2019/08/12)
A variety of arenes and heteroarenes are chlorinated in moderate to excellent yields using N-chlorosuccinimide (NCS) under visible-light activated conditions. A screening of known organic dye photocatalysts resulted in the identification of methylene green as the most efficient catalyst to use with NCS. According to mechanistic studies described within, the reaction is speculated to proceed via a single electron oxidation of NCS utilizing methylene green under visible-light photoredox pathway. The photo-oxidation of NCS amplifies the electrophilicity of the chlorine atom of the NCS, thus leading to enhanced reactivity as a chlorinating reagent with aromatic substrates.
Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
-
, (2008/06/13)
The present invention concerns antiviral compounds, their methods of preparation and their compositions, and use in the treatment of viral infections. More particularly, the invention provides heterocyclic substituted 2-methylbenzimidazole derivatives for the treatment of respiratory syncytial virus infection.