2930-02-1

Basic information

• Product Name: 2-(p-Ethylphenoxymethyl)oxirane
• Synonyms: 2-(p-Ethylphenoxymethyl)oxirane;4-Ethylphenylglycidyl ether;[(4-Ethylphenoxy)Methyl]oxirane;1,2-Epoxy-3-(p-ethylphenoxy)propane;2,3-Epoxypropyl 4-Ethylphenyl Ether;p-Ethylphenyl Glycidyl Ether
• CAS NO: 2930-02-1
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.23
• Product Categories: Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 2930-02-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(p-Ethylphenoxymethyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(p-Ethylphenoxymethyl)oxirane(2930-02-1)
• EPA Substance Registry System: 2-(p-Ethylphenoxymethyl)oxirane(2930-02-1)

Safety Data

• Hazardous Substances Data: 2930-02-1(Hazardous Substances Data)

Usage

Description

2-(p-Ethylphenoxymethyl)oxirane is an organic compound belonging to the class of epoxides. It is characterized by the presence of a three-membered oxirane ring, which is a cyclic ether with an oxygen atom and two carbon atoms. 2-(p-Ethylphenoxymethyl)oxirane has a p-ethylphenoxymethyl group attached to the second carbon of the oxirane ring, which may contribute to its specific properties and applications.

Uses

Used in Pesticide Industry:
2-(p-Ethylphenoxymethyl)oxirane is used as an active ingredient for [application reason] due to its enzyme epoxide hydrase inhibitory effects. This property makes it a potential candidate for the development of new pesticides, as it can interfere with the normal functioning of target pests, leading to their control and management in agricultural settings.

Upstream product

• 123-07-9 4-Ethylphenol 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 106-89-8 epichlorohydrin 

Downstream Products

• 437994-25-7 7,7,9,9-tetramethyl-8-[1-(4-oxiranylmethoxy-phenyl)-ethoxy]-1,4-dioxa-8-aza-spiro[4.5]decan 
• 1254940-27-6 C₂₈H₃₂N₄O₂S 

Relevant articles and documents

Regioselective ring-opening of epoxides by carbazole: A direct preparation of novel N-(β-hydroxyalkyl)carbazoles

The influence of various parameters including solvent, base and temperature on the reaction between carbazole and epoxides was studied This led to the development of a regioselective ring-opening of epoxides by the potassium salt of carbazole in DMSO at 100 °C which is a straightforward way to prepare new N-(β-hydroxyalkyl)carbazoles in good to excellent yields. Fifteen new compounds are described.

Thienopyrimidines as β3-adrenoceptor agonists: Hit-to-lead optimization

Resulting from a vHTS based on a pharmacophore alignment on known β3-adrenoceptor ligands, an aryloxypropanolamine scaffold comprising a thienopyrimidine moiety was further optimized as a human β3-AR agonist, yielding a lead compound with an excellent cellular activity of EC50 = 20 pM, selectivity over hβ1- and hβ2-adrenoceptors and a promising safety profile.