29484-23-9

Basic information

• Product Name: costunolide 1,10-epoxide
• CAS NO: 29484-23-9
• Molecular Weight: 248.322
• Mol File: 29484-23-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: costunolide 1,10-epoxide(CAS DataBase Reference)
• NIST Chemistry Reference: costunolide 1,10-epoxide(29484-23-9)
• EPA Substance Registry System: costunolide 1,10-epoxide(29484-23-9)

Safety Data

• Hazardous Substances Data: 29484-23-9(Hazardous Substances Data)

Upstream product

• 553-21-9 costunolide 

Downstream Products

• 29424-04-2 (+)-reynosin 
• 32223-12-4 11β,13-dihydroreynosin 
• 4290-13-5 santamarine 

Relevant articles and documents

Absolute stereostructures and syntheses of saussureamines A, B, C, D and E, amino acid-sesquiterpene conjugates with gastroprotective effect, from the roots of Saussurea lappa

From the methanolic extract of the dried roots of Saussurea lappa Clarke, Saussureae Radix, five amino acid-sesquiterpene conjugates, saussureamines A, B, C, D and E, were isolated together with a lignan glycoside, (-)-massoniresinol 4-O-β-D-glucopyranoside. Their stereostructures were determined on the basis of chemical and physicochemical evidence. In addition, saussureamines and the related amino acid-sesquiterpene conjugates were synthesized using a Michael type addition reaction of amino acid to the α-methylene-γ-lactone moiety of sesquiterpenes. Saussureamines A, B and C, costunolide and dehydrocostus lactone showed a gastroprotective effect on acidified ethanol-induced gastric mucosal lesions in rats. Saussureamines A also exhibited an inhibitory effect on gastric mucosal lesions induced by water-immersion stress in mice. (C) 2000 Elsevier Science Ltd.