2952-05-8Relevant articles and documents
Thermal azide-Alkene cycloaddition reactions: straightforward multi-gram access to Δ2-1,2,3-Triazolines in deep eutectic solvents
Sebest, Filip,Casarrubios, Luis,Rzepa, Henry S.,White, Andrew J. P.,Díez-González, Silvia
supporting information, p. 4023 - 4035 (2018/09/11)
The multi-gram synthesis of a wide range of 1,2,3-Triazolines via azide-Alkene cycloaddition reactions in a Deep Eutectic Solvent (DES) is reported. The role of DES in this transformation as well as the origin of the full product distribution was studied with an experimental/computational-DFT approach.
Direct conversion of epoxides into aziridines with N-arylphosphoramidates
Minicone, Fabrizio,Rogers, Wendy J.,Green, James F.J.,Khan, Mommna,Smith, Geoffrey M.T.,Bray, Christopher D.
, p. 5890 - 5891 (2014/12/12)
Treatment of terminal epoxides with N-arylphosphoramidate anions leads directly to N-aryl aziridines. Existing methods for this transformation employ either multi-step syntheses or an iminophosphorane in conjunction with a Lewis acid. The described method therefore presents an advantage in terms of brevity and atom economy.
Novel aziridination of α-halo ketones: an efficient nucleophile-induced cyclization of phosphoramidates to functionalized aziridines
Yadav, Lal Dhar S.,Rai, Ankita,Rai, Vijai K.,Awasthi, Chhama
, p. 687 - 690 (2008/09/17)
A novel and efficient aziridination of α-halo ketones is reported. The reaction of α-halo ketones with diethyl N-arylphosphoramidates affords diethyl N-aryl-N-(2-oxoalkyl)phosphoramidates which undergo reductive (H--induced) cyclization with so