29560-84-7

Basic information

• Product Name: 3-chloroallyl alcohol
• Synonyms: 3-chloroallyl alcohol;3-Chloro-2-propen-1-ol;3-chloroprop-2-en-1-ol;3-Chloro-2-propen-1-ol (E/Z Mixture)
• CAS NO: 29560-84-7
• Molecular Formula: C₃H₅ClO
• Molecular Weight: 92.53
• Mol File: 29560-84-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 84.72°C (rough estimate)
• Flash Point: 30.4°C
• Appearance: /
• Density: 1.1769
• Vapor Pressure: 5.29mmHg at 25°C
• Refractive Index: 1.4738 (estimate)
• CAS DataBase Reference: 3-chloroallyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloroallyl alcohol(29560-84-7)
• EPA Substance Registry System: 3-chloroallyl alcohol(29560-84-7)

Safety Data

• Hazardous Substances Data: 29560-84-7(Hazardous Substances Data)

Usage

Description

3-Chloro-2-propen-1-ol, commonly known as 3-chloroallyl alcohol, is an organic compound that serves as a significant metabolite of 1,3-Dichloropropene (D436510). It is characterized by its unique chemical structure, which includes a chlorine atom attached to a three-carbon chain with a hydroxyl group. This structure endows 3-chloroallyl alcohol with specific properties that make it valuable in various applications.

Uses

Used in Pharmaceutical Industry:
3-Chloroallyl alcohol is used as a key intermediate in the synthesis of Tafuramycin A, a potent anticancer and parasite attenuating agent. Its role in the production of this therapeutic compound highlights its importance in the development of treatments for cancer and parasitic infections.
Used in Chemical Synthesis:
3-Chloroallyl alcohol is utilized as a reagent in various chemical synthesis processes due to its reactive functional groups. Its ability to participate in a range of chemical reactions, such as substitution, addition, and elimination, makes it a versatile building block for creating a variety of compounds with different applications in the chemical and pharmaceutical industries.

InChI:InChI=1/C3H5ClO/c4-2-1-3-5/h1-2,5H,3H2/b2-1+

Upstream product

• 542-75-6 E/Z-1,3-Dichloropropene 
• 26438-85-7 3-chloro-2-fluoro-1-propanol 
• 64-17-5 ethanol 
• 563-57-5 3,3-dichloropropene 
• 4643-05-4 (Z)-1-Chloro-1-propene-3-ol 
• 10061-01-5 cis-1,3-Dichloropropene 

Downstream Products

• 64058-39-5 lactic acid-(3-chloro-allyl ester) 
• 91552-27-1 phenyl-carbamic acid-(3-chloro-allyl ester) 
• 6288-10-4 acrylic acid-(3-chloro-allyl ester) 
• 29516-63-0 2-((E)-3-Chloro-allyloxy)-1-methyl-3,5-dinitro-benzene 
• 63270-87-1 N,N-di-n-propyl-3-aminopropenaldehyde 
• 107-19-7 propargyl alcohol 
• 627-30-5 1-chloro-3-hydroxypropane 

Relevant articles and documents

Method and system for producing 1, 3-propylene glycol by multi-step method

The invention discloses a method and a system for producing 1, 3-propylene glycol by a multi-step method. The method comprises the following steps: carrying out dehydration reaction on 1, 3-dichloropropanol and a dehydration catalyst to prepare 1, 3-dichloropropene; carrying out a first hydrolysis reaction on a first mixed reaction system containing the 1, 3-dichloropropene, a first hydrolysis agent and a first solvent to prepare 3-chloro-2-propene-1-alcohol; carrying out hydrogenation reaction on the 3-chloro-2-propene-1-alcohol and a hydrogenation catalyst to prepare 3-chloropropanol; and carrying out a second hydrolysis reaction on a second mixed reaction system containing the 3-chloropropanol, a second hydrolysis agent and a second solvent to prepare the 1, 3-propylene glycol. According to the method, 1, 3-dichloropropanol is used as a raw material, the important chemical raw material 1, 3-propylene glycol is prepared through a dehydration, hydrolysis, hydrogenation and hydrolysisfour-step method, and the method has the advantages of mild reaction conditions, low cost, environmental protection, economy and the like.

Novel photoreaction using diphenyl disulfide derivatives: Photoinduced oxidation of allyl alcohol

Allyl alcohols are oxidized to acrylaldehydes using diphenyl disulfide derivatives upon photoirradiation. The reaction occurs via α-hydrogen abstraction by a sulfanyl radical. Interestingly, the oxidation reaction occurs in moderate yield when a dendrimer disulfide is used as a mediator.