297773-48-9

Basic information

• Product Name: 3-AMINO-3-(6-CHLORO-PYRIDIN-3-YL)-PROPIONIC ACID
• Synonyms: 3-AMINO-3-(6-CHLORO-PYRIDIN-3-YL)-PROPIONIC ACID;RARECHEM AK ML 0096
• CAS NO: 297773-48-9
• Molecular Formula: C8H9ClN2O2
• Molecular Weight: 200.62
• Mol File: 297773-48-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 391.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.403±0.06 g/cm3(Predicted)
• PKA: 3.19±0.12(Predicted)
• CAS DataBase Reference: 3-AMINO-3-(6-CHLORO-PYRIDIN-3-YL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-(6-CHLORO-PYRIDIN-3-YL)-PROPIONIC ACID(297773-48-9)
• EPA Substance Registry System: 3-AMINO-3-(6-CHLORO-PYRIDIN-3-YL)-PROPIONIC ACID(297773-48-9)

Safety Data

• Hazardous Substances Data: 297773-48-9(Hazardous Substances Data)

Upstream product

• 23100-12-1 6-chloronicotinylaldehyde 
• 141-82-2 malonic acid 

Downstream Products

• 252989-87-0 N-Boc-3-amino-3-(6-chloro-3-pyridyl)propionic acid 
• 297773-52-5 (S)-N-Boc-3-amino-3-(6-chloro-3-pyridyl)propionic acid 

Relevant articles and documents

An expedient method for resolution of 3-amino-3-(3′-pyridyl)propionic acid and related compounds

Preparation of methyl (S)-3-amino-3-(3′-pyridyl)propionate dihydrochloride in high enantiomeric purity by selective crystallization of a diastereomeric salt of a carboxylic acid precursor (W-BOC-protected) with (1R,2S)-(-)-ephedrine is described. Further demonstration of the usefulness of this procedure to resolve other 3-amino-3-[(substituted)pyridyl]propionic acids is also described.