29786-44-5

Basic information

• Product Name: 1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile
• Synonyms: 1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile
• CAS NO: 29786-44-5
• Molecular Formula: C₁₂H₁₀F₃N
• Molecular Weight: 225.2097096
• Mol File: 29786-44-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile(29786-44-5)
• EPA Substance Registry System: 1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile(29786-44-5)

Safety Data

• Hazardous Substances Data: 29786-44-5(Hazardous Substances Data)

Usage

General Description

1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile is a chemical compound with the molecular formula C11H8F3N. It is a colorless liquid with a molecular weight of 221.18 g/mol. 1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile is commonly used in organic synthesis and pharmaceutical research due to its unique chemical structure and properties. It is also used as an intermediate in the production of various pharmaceuticals and agrochemicals. Additionally, 1-(4-(trifluoroMethyl)phenyl)cyclobutanecarbonitrile has been studied for its potential bioactivity and pharmacological properties. However, it is important to handle and use this compound with caution, as it may pose health and safety risks if not properly managed.

Upstream product

• 109-64-8 1,3-dibromo-propane 
• 2338-75-2 4-(Trifluoromethyl)phenylacetonitrile 

Downstream Products

• 29786-54-7 1-(4-(trifluoromethyl)phenyl)cyclobutane-1-carboxamide 
• 29770-27-2 <1-(α,α,α-Trifluor-p-tolyl)-cyclobutyl>-carbonylisocyanat 
• 29770-40-9 (<1-(α,α,α-Trifluor-p-tolyl)-cyclobutyl>-carbonyl)-harnstoff 
• 29786-23-0 (<1-(α,α,α-Trifluoro-p-tolyl)cyclobutyl>carbonyl)carbamsaeuremethylester 
• 29786-32-1 (<1-(α,α,α-Trifluoro-p-tolyl)cyclobutyl>carbonyl)carbamsaeureethylester 
• 1432050-06-0 (2-aminocyclopentyl){1-[4-(trifluoromethyl)phenyl]cyclobutyl}methanol 
• 1432492-84-6 2-(hydroxy(1-(4-(trifluoromethyl)phenyl)cyclobutyl)methyl)cyclopentanone 
• 1086379-78-3 1-(4-(trifluoromethyl)phenyl)cyclobutane-1-carboxylic acid 

Relevant articles and documents

Iridium-Catalyzed Enantioselective C(sp3)–H Borylation of Cyclobutanes

We herein report the first example of iridium-catalyzed enantioselective C(sp3)–H borylation of cyclobutanes using benzoxazoline as the directing group. The combination of a chiral bidentate boryl ligand and an iridium precursor has found to effectively catalyze C(sp3)–H borylation to afford a variety of cyclobutylboronates with good to excellent enantioselectivities. We also demonstrate the synthetic utility of the current method by converting the stereogenic C—B bond to other functionalities.

PYRIMIDONE CARBOXAMIDE COMPOUNDS AS PDE2 INHIBITORS

Disclosed are pyrimidine carboxamide compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2), pharmaceutical compositions and uses thereof.

NOVEL TRPV3 MODULATORS

Disclosed herein are modulators of TRPV3 of formula (II): wherein G1, X1, X2, X3, X4, X5, G2, Ra, Rb, and u are as defined in the specification. Composition