29816-55-5

Basic information

• Product Name: 1-(4-Methylphenyl)-2-nitropropene
• Synonyms: 1-(4-METHYLPHENYL)-2-NITROPROPENE, >95%;1-(4-Methylphenyl)-2-nitropropene;4-Metyl-1-phenyl-2-nitropropene;1-Methyl-4-(2-nitroprop-1-en-1-yl)benzene
• CAS NO: 29816-55-5
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.2
• Mol File: 29816-55-5.mol
• Article Data: 13

Chemical Properties

• Melting Point: 55 °C
• Boiling Point: 282.7 °C at 760 mmHg
• Flash Point: 123.9 °C
• Appearance: /
• Density: 1.112 g/cm³
• Vapor Pressure: 0.00563mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 1-(4-Methylphenyl)-2-nitropropene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Methylphenyl)-2-nitropropene(29816-55-5)
• EPA Substance Registry System: 1-(4-Methylphenyl)-2-nitropropene(29816-55-5)

Safety Data

• Hazardous Substances Data: 29816-55-5(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow crystalline powder

InChI:InChI=1/C10H11NO2/c1-8-3-5-10(6-4-8)7-9(2)11(12)13/h3-7H,1-2H3/b9-7+

Upstream product

• 79-24-3 Nitroethane 
• 104-87-0 4-methyl-benzaldehyde 
• 135711-44-3 Butyl-(2-nitro-1-p-tolyl-propyl)-amine 
• 53982-05-1 2-nitro-1-(p-tolyl)propan-1-ol 
• 104-84-7 para-methylbenzylamine 

Downstream Products

• 64-11-9 4-methylamphetamine 
• 2096-86-8 p-Tolylaceton 
• 29865-50-7 1-(4'-methylphenyl)-2-nitropropane 
• 98450-35-2 5-<<1-(tert-Butoxycarbonyl)-2-oxopropyliden>amino>-4,5-dihydro-2,5-dimethyl-4-(4-tolyl)-3-furancarbonsaeure-tert-butylester 
• 130888-89-0 (1-Hydroxy-2,6-dimethyl-1H-indol-3-yl)-phosphonic acid diisopropyl ester 
• 130888-92-5 (1-Hydroxy-2,6-dimethyl-1H-indol-3-yl)-phenyl-phosphinic acid isopropyl ester 
• 124901-13-9 ethyl 4-methyl-3-(p-tolyl)-2-pyrrolecarboxylate 
• 124344-85-0 1,4-dimethyl-3-(D-manno-pentitol-1-yl)-5-(p-tolyl)pyrazole 
• 124344-85-0 1,4-dimethyl-3-(D-galacto-pentitol-1-yl)-5-(p-tolyl)pyrazole 
• 58949-75-0 4-(2-oxopropyl)benzonitrile 
• 1723-25-7 ethyl 2,3-dioxobutyrate 
• 95838-66-7 2,5-Dimethyl-4-(4-tolyl)-3-pyrrolcarbonsaeure-ethylester 
• 95838-80-5 5-<<1-(Ethoxycarbonyl)-2-oxopropyliden>amino>-4,5-dihydro-2,5-dimethyl-4-(4-tolyl)-3-furancarbonsaeure-ethylester 
• 98450-30-7 4,5-Dihydro-5-<<1-(methoxycarbonyl)-2-oxopropyliden>amino>-2,5-dimethyl-4-(4-tolyl)-3-furancarbonsaeure-methylester 

Relevant articles and documents

A diversity-oriented synthesis of polyheterocycles: Via the cyclocondensation of azomethine imine

Pd-Catalyzed sequential reactions to afford skeletally diverse molecules are described. The reaction involved azomethine imine formation and a cyclocondensation reaction as individual steps. The methodology provides excellent regio- and stereocontrol. Skeletal diversity was ensured by changing the electrophilic counterpart of azomethine imine. Due to its broader diversity and complexity, the DOS methodology is likely to benefit drug discovery and development in the future.

Synthesis of Benzo[4,5]imidazo[2,1-b]thiazole by Copper(II)-Catalyzed Thioamination of Nitroalkene with 1H-Benzo[d]imidazole-2-thiol

A Copper(II)-catalyzed thioamination of β-nitroalkene with 1H-benzo[d]imidazole-2-thiol has been developed for the synthesis of benzo[4,5]imidazo[2,1-b]thiazole derivatives. A variety of N-fused benzoimidazothiazole derivatives are obtained in high yields through successive C?N and C?S bond formations. This protocol is also applicable to β-substituted β-nitroalkenes to afford 2,3-disubstituted benzoimidazothiazoles. (Figure presented.).

Dynamic kinetic asymmetric ring-opening/reductive amination sequence of racemic nitroepoxides with chiral amines: Enantioselective synthesis of chiral vicinal diamines

We report a highly diastereoselective synthesis of vicinal diamines by the treatment of nitroepoxides with primary amines and then a reducing agent. When using a chiral primary amine, racemic nitroepoxides are transformed into chiral diamines as a single enantiomers (>95:5 er) through a dynamic kinetic asymmetric transformation (DYKAT). The overall process is a one-pot procedure combining the exposure of nitroepoxides to chiral amines to afford diastereomeric mixtures of aminoimines and subsequent stereoselective imine reduction.