29865-54-1

Basic information

• Product Name: Benzene, 1-chloro-4-(2-nitropropyl)-
• CAS NO: 29865-54-1
• Molecular Formula: C9H10ClNO2
• Molecular Weight: 199.637
• Mol File: 29865-54-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-(2-nitropropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-(2-nitropropyl)-(29865-54-1)
• EPA Substance Registry System: Benzene, 1-chloro-4-(2-nitropropyl)-(29865-54-1)

Safety Data

• Hazardous Substances Data: 29865-54-1(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 710-20-3 1-chloro-4-(2-nitropropenyl)benzene 
• 79-24-3 Nitroethane 
• 873-76-7 para-Chlorobenzyl alcohol 
• 37629-52-0 (E)-1-(4-chlorophenyl)-2-nitropropene 
• 71017-85-1 1-(4-chlorobenzyl)-2,4,6-triphenylpyridin-1-ium tetrafluoroborate 

Downstream Products

• 5586-88-9 1-(4-chlorophenyl)propan-2-one 
• 623-03-0 4-Cyanochlorobenzene 

Relevant articles and documents

Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water

An iridium-catalyzed highly chemoselective and efficient transfer hydrogenation reduction of structurally diverse nitroalkenes was realized at very low catalyst loading (S/C = up to 10000 or 20?000), using formic acid or sodium formate as a traceless hydride donor in water. Excellent functionality tolerance is also observed. The turnover number and turnover frequency of the catalyst reach as high as 18?600 and 19?200 h-1, respectively. An inert atmosphere protection is not required. The reactivities of nitroalkenes are dependent on their substitution pattern, and the pH value is a key factor to accomplish the complete conversion and excellent chemoselectivity. Purification of products is achieved by simple extraction without column chromatography. The reduction procedure is facilely amplified to 10 g scale at 10?000 S/C ratio. The potential of this green reduction in enantioselective hydrogenation has been demonstrated.

The highly chemoselective transfer hydrogenation of the carbon-carbon double bond of conjugated nitroalkenes by a rhodium complex

Chemoselective transfer hydrogenation of conjugated nitroalkenes catalyzed by [RhCl2Cp·]2-diamine complex (Cp ·=η5-C5Me5) using HCOOH/Et3N (5:2) (TEAF) as a hydrogen source was realized. A variety of nitrostyrenes, β-methyl nitrostyrenes, and 3-methyl-4-nitro-5-alkenyl- isoxazoles were reduced smoothly in good to excellent yields in short reaction time. Other functional groups are inert under the reaction conditions.

Borrowing hydrogen: Iridium-catalysed reactions for the formation of C-C bonds from alcohols

Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond. The Royal Society of Chemistry 2006.