29899-95-4

Basic information

• Product Name: Clobenoside
• Synonyms: clobenoside;(3R,4R,5R)-5-[(1R)-1,2-Bis[(4-chlorophenyl)methoxy]ethyl]-2-ethoxy-4-propoxyoxolan-3-ol;Ethyl 5,6-bis-O-(p-chlorobenzyl)-3-O-propyl-D-glucofuranoside;43853;Ethyl 5-O,6-O-bis(4-chlorobenzyl)-3-O-propyl-D-glucofuranoside;Ethyl 5-O,6-O-bis[(4-chlorophenyl)methyl]-3-O-propyl-D-glucofuranoside
• CAS NO: 29899-95-4
• Molecular Formula: C25H32Cl2O6
• Molecular Weight: 499.42
• EINECS: 249-940-5
• Mol File: 29899-95-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 602°C at 760 mmHg
• Flash Point: 317.9°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 2.42E-15mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: Clobenoside(CAS DataBase Reference)
• NIST Chemistry Reference: Clobenoside(29899-95-4)
• EPA Substance Registry System: Clobenoside(29899-95-4)

Safety Data

• Hazardous Substances Data: 29899-95-4(Hazardous Substances Data)

Usage

Description

Clobenoside, also known as Arvigol, is a vasoprotective agent with potent anti-inflammatory properties. It is primarily derived from the saponin fraction of the Yucca schidigera plant and has been found to be effective in various medical applications due to its ability to inhibit histamine and kinins, as well as its vasoprotective and anti-inflammatory characteristics.

Uses

Used in Pharmaceutical Industry:
Clobenoside is used as a therapeutic agent for the topical treatment of chronic venous insufficiency and post-thrombotic syndrome. Its vasoprotective and anti-inflammatory properties help alleviate the symptoms associated with these conditions, improving the overall health and well-being of patients.
Used in Anti-inflammatory Applications:
Clobenoside is utilized as an anti-inflammatory agent, particularly effective in treating traumatic edema. It exerts its effects by inhibiting the release of histamine and/or kinins, which are responsible for the inflammation and swelling observed in various traumatic conditions.
Used in Cosmetic Industry:
Clobenoside can also be used in the cosmetic industry as an ingredient in skincare products due to its anti-inflammatory and vasoprotective properties. It may help reduce inflammation, soothe irritated skin, and improve overall skin health.

Originator

Ciba Geigy (Switzerland)

InChI:InChI=1/C25H32Cl2O6/c1-3-13-31-24-22(28)25(30-4-2)33-23(24)21(32-15-18-7-11-20(27)12-8-18)16-29-14-17-5-9-19(26)10-6-17/h5-12,21-25,28H,3-4,13-16H2,1-2H3/t21-,22-,23-,24-,25?/m1/s1