29913-84-6 Usage
Description
S-Methyl-D-penicillamine is a biochemical transformed metabolite derived from D-Penicillamine (P223000). It has been identified in elevated levels in the urine of patients suffering from Parkinson's and Motor Neuron Disease, indicating its potential significance in the study and understanding of these neurological conditions.
Uses
Used in Neurological Research:
S-Methyl-D-penicillamine is used as a biomarker for the detection and monitoring of Parkinson's and Motor Neuron Disease patients. The elevated levels of this metabolite in the urine of affected individuals provide valuable insights into the pathophysiology of these conditions and may contribute to the development of diagnostic tools and therapeutic strategies.
Used in Pharmaceutical Development:
Given its association with specific neurological diseases, S-Methyl-D-penicillamine may be utilized as a starting point for the development of novel pharmaceuticals targeting Parkinson's and Motor Neuron Disease. Its unique biochemical properties could be harnessed to create targeted therapies that address the underlying causes of these conditions.
Used in Diagnostic Applications:
S-Methyl-D-penicillamine can be employed as a diagnostic agent to identify and differentiate between Parkinson's and Motor Neuron Disease patients. The measurement of its levels in urine samples could serve as a non-invasive diagnostic method to aid in the early detection and accurate diagnosis of these neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 29913-84-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,9,1 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 29913-84:
(7*2)+(6*9)+(5*9)+(4*1)+(3*3)+(2*8)+(1*4)=146
146 % 10 = 6
So 29913-84-6 is a valid CAS Registry Number.
29913-84-6Relevant articles and documents
The species- and site-specific acid-base properties of penicillamine and its homodisulfide
Mirzahosseini, Arash,Szilvay, András,Noszál, Béla
, p. 62 - 69 (2015/04/14)
Penicillamine, penicillamine disulfide and 4 related compounds were studied by 1H NMR-pH titrations and case-tailored evaluation methods. The resulting acid-base properties are quantified in terms of 14 macroscopic and 28 microscopic protonation constants and the concomitant 7 interactivity parameters. The species- and site-specific basicities are interpreted by means of inductive and shielding effects through various intra- and intermolecular comparisons. The thiolate basicities determined this way are key parameters and exclusive means for the prediction of thiolate oxidizabilities and chelate forming properties in order to understand and influence chelation therapy and oxidative stress at the molecular level.
Acyclic metalloprotease inhibitors
-
, (2008/06/13)
The invention provides compounds of formula as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metallop
