30058-47-0

Basic information

• Product Name: (4,5-dimethoxy-2-nitrophenyl)(phenyl)sulfane
• Synonyms: (4,5-dimethoxy-2-nitrophenyl)(phenyl)sulfane
• CAS NO: 30058-47-0
• Molecular Weight: 291.328
• Mol File: 30058-47-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4,5-dimethoxy-2-nitrophenyl)(phenyl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-dimethoxy-2-nitrophenyl)(phenyl)sulfane(30058-47-0)
• EPA Substance Registry System: (4,5-dimethoxy-2-nitrophenyl)(phenyl)sulfane(30058-47-0)

Safety Data

• Hazardous Substances Data: 30058-47-0(Hazardous Substances Data)

Upstream product

• 51072-66-3 1-bromo-4,5-dimethoxy-2-nitro-benzene 
• 108-98-5 thiophenol 
• 4101-32-0 4',5'-dimethoxy-2'-nitroacetophenone 
• 37942-55-5 1-(4,5-Dimethoxy-2-nitrophenyl)-ethanol 
• 882-33-7 diphenyldisulfane 
• 4998-07-6 4,5-dimethoxy-2-nitro-benzoic acid 

Downstream Products

• 30072-78-7 N-(2-Diethylamino-ethyl)-N-(4,5-dimethoxy-2-phenylsulfanyl-phenyl)-N',N'-diethyl-ethane-1,2-diamine 
• 73775-87-8 C₁₉H₂₅N₃O₄S 
• 68560-04-3 6,7-dimethoxy-1-oxo-1-phenyl-4H-1λ⁶-benzo[1,2,4]thiadiazin-3-one 
• 30058-48-1 2-Phenylthio-4,5-dimethoxyaniline 

Relevant articles and documents

Synthesis of thioethers, arenes and arylated benzoxazoles by transformation of the C(aryl)-C bond of aryl alcohols

Transformation of aryl alcohols into high-value functionalized aromatic compounds by selective cleavage and functionalization of the C(aryl)-C(OH) bond is of crucial importance, but very challenging by far. Herein, for the first time, we report a novel and versatile strategy for activation and functionalization of C(aryl)-C(OH) bonds by the cooperation of oxygenation and decarboxylative functionalization. A diverse range of aryl alcohol substrates were employed as arylation reagents via the cleavage of C(aryl)-C(OH) bonds and effectively converted into corresponding thioether, arene, and arylated benzoxazole products in excellent yields, in a Cu based catalytic system using O2 as the oxidant. This study offers a new way for aryl alcohol conversion and potentially offers a new opportunity to produce high-value functionalized aromatics from renewable feedstocks such as lignin which features abundant C(aryl)-C(OH) bonds in its linkages.

Synthesis and blood pressure lowering activity of 3-(substituted-amino)-1,2,4-benzothiadazine 1-oxide derivatives

A series of (substituted amino)-1,2,4-benzothiadiazine 1-oxides has been synthesized and most members of the series have been shown to have blood-pressure lowering effects in normotensive rabbits and in spontaneously hypertensive rats. The most active member of the series was 3-[4-(2-furoyl)-1-piperazinyl]-6,7-dimethoxy-1-methyl-1H-1,2,4-benzothiadiazine 1-oxide hydrochloride. This compound in animal tests was equipotent to the known antihypertensive Prazosin.