3010-09-1Relevant articles and documents
Controllable access to multi-substituted imidazoles: Via palladium(II)-catalyzed C-C coupling and C-N condensation cascade reactions
Yu, Haihua,Xiao, Li,Yang, Xicheng,Shao, Liming
supporting information, p. 9745 - 9748 (2017/09/07)
A novel and efficient protocol for the synthesis of various 2,4-disubstituted, 1,2,4-trisubstituted and 1,2,4,5-tetra-substituted imidazoles via cascade palladium catalyzed C-C coupling followed by intramolecular C-N bond formation was developed. Readily accessible boronic acids and N-substituted-2-aminoacetonitriles were firstly reported as starting materials to construct di-, tri-, and tetra-substituted imidazoles in good to excellent yield.
RuO4-mediated oxidation of secondary amines. Part 1. Are hydroxylamines the main intermediates?
Florea, Cristina A.,Petride, Horia
, p. 475 - 486 (2016/07/20)
The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a and b; R=H, Me) gave mainly amides, but minute amounts of nitrones PhCH=N(O)-CH2R (9a and b) and traces of Bn-N(OH)-CH2R (R=H, 4a) were also detect
A new entry to [1,2,4]triazolo[1,5-α][1,4]benzodiazepin-6-ones via intramolecular nitrilimine cycloaddition to the cyano group
Broggini, Gianluigi,Garanti, Luisa,Molteni, Giorgio,Zecchi, Gaetano
, p. 14859 - 14868 (2007/10/03)
A series of [1,2,4]triazolo[1,5-α][1,4]benzodiazepin-6-ones of potential pharmacological interest have been synthesised by means of intramolecular nitrilimine cycloadditions to the cyano group.