30152-05-7

Basic information

• Product Name: Ethanone, 1-(3-hydroxy-4-pyridinyl)- (9CI)
• Synonyms: Ethanone, 1-(3-hydroxy-4-pyridinyl)- (9CI);1-(3-Hydroxypyridin-4-yl)ethanone;Ethanone, 1-(3-hydroxy-4-pyridinyl)-;1-(3-Hydroxy-4-pyridinyl)ethanone;3-hydroxy-4-pyridylmethyl ketone;1-(3-Hydroxypyridin-4-yl)
• CAS NO: 30152-05-7
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 137.13598
• Product Categories: ACETYLGROUP
• Mol File: 30152-05-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 52-54℃
• Boiling Point: 336.468 °C at 760 mmHg
• Flash Point: 157.291 °C
• Appearance: /
• Density: 1.218 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 6.90±0.10(Predicted)
• CAS DataBase Reference: Ethanone, 1-(3-hydroxy-4-pyridinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3-hydroxy-4-pyridinyl)- (9CI)(30152-05-7)
• EPA Substance Registry System: Ethanone, 1-(3-hydroxy-4-pyridinyl)- (9CI)(30152-05-7)

Safety Data

• Hazardous Substances Data: 30152-05-7(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(3-hydroxy-4-pyridinyl)- (9CI) is a chemical compound that belongs to the class of ketones and is also known by its systematic name 3-Hydroxy-4-pyridin-3-ylacetone. It is a pale yellow solid with a molecular formula of C7H7NO2. Ethanone, 1-(3-hydroxy-4-pyridinyl)- (9CI) is commonly used in the synthesis of pharmaceuticals and agrochemicals as well as in organic chemistry research. It is also known to have biological activity and may have potential applications in the development of new drugs. Additionally, it is important to handle this chemical with care due to its potential hazards and toxicity.

Upstream product

• 1089689-12-2 1-(3-(methoxymethoxy)pyridin-4-yl)ethanone 
• 1089707-46-9 1-(3-(methoxymethoxy)pyridin-4-yl)ethanol 
• 81245-25-2 3-(methoxymethoxy)pyridine 
• 109-00-2 3-HYDROXYPYRIDINE 
• 59786-32-2 methyl 3-methoxy-4-pyridinecarboxylate 
• 83431-02-1 1-(3-methoxypyridin-4-yl)-ethanone 
• 15031-12-6 5-ethoxyoxazole 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 83431-05-4 2-methyloxozalo<5,4-c>pyridine 
• 83431-06-5 3-methylisooxozolo<5,4-c>pyridine 
• 83431-04-3 1-(3-Hydroxy-pyridin-4-yl)-ethanone oxime 
• 106531-57-1 3-Methyl-furo[2,3-c]pyridine 

Relevant articles and documents

CONDENSED TRICYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

There is provided compounds of formula I, (I) wherein R1, R2, R3 R4, R5, R6, R7a and R7b have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. CDK8 and/or Haspin kinase) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.

Oxazoles in Diels-Alder Reactions. Transformation of The Adducts to Either Pyridines or Pyrroles

The cycloadducts between acrylic acid or acrylonitrile and 5-ethoxyoxazoles are converted as formed to 3-hydroxypyridines.The Diels-Alder adducts from ethyl acrylate, or methyl or phenyl vinyl ketone can be isolated.In ethanolic HCl the adducts are transformed into 3-hydroxypyridines; in aqueous HCl the products are acylpyrrole analogues.A 4-substituent in the oxazole affects the reaction. 4-Methyl-5-ethoxyoxazole reacts much faster than its 5-ethylthio analogue.