301692-94-4

Basic information

• Product Name: 4-(3-(3,4-difluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide
• Synonyms: 4-(3-(3,4-difluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide;4-[3-(3,4-difluorophenyl)-5,5-diMethyl-4-oxo-4,5-dihydrofuran-2-yl]benzene-1-sulfonaMide
• CAS NO: 301692-94-4
• Molecular Formula: C18H15F2NO4S
• Molecular Weight: 379
• Mol File: 301692-94-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 210-211 °C
• Boiling Point: 524.6±60.0 °C(Predicted)
• Appearance: /
• Density: 1.406±0.06 g/cm3(Predicted)
• PKA: 10.21±0.10(Predicted)
• CAS DataBase Reference: 4-(3-(3,4-difluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-(3,4-difluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide(301692-94-4)
• EPA Substance Registry System: 4-(3-(3,4-difluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide(301692-94-4)

Safety Data

• Hazardous Substances Data: 301692-94-4(Hazardous Substances Data)

Relevant articles and documents

4,5-diaryl-3(2H)-furanone derivatives as cyclooxygenase-2 inhibitors

The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.