3018-68-6 Usage
General Description
2-Methyl-1-phenyl-1H-benzimidazol-5-amine hydrochloride is a chemical compound with the molecular formula C14H14N3Cl. It is a hydrochloride salt form of 2-methyl-1-phenyl-1H-benzimidazol-5-amine, a benzimidazole derivative. 2-METHYL-1-PHENYL-1H-BENZIMIDAZOL-5-AMINE HYDROCHLORIDE has been studied for its potential medicinal properties, particularly in the field of oncology. It has shown promise as a potential antineoplastic agent, with studies demonstrating its ability to inhibit the growth of cancer cells. Additionally, it has also been investigated for its potential as an antimicrobial agent. The hydrochloride salt form of this compound is a crystalline solid that is soluble in water and organic solvents, making it suitable for various pharmaceutical and research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3018-68-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,1 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3018-68:
(6*3)+(5*0)+(4*1)+(3*8)+(2*6)+(1*8)=66
66 % 10 = 6
So 3018-68-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H13N3/c1-10-16-13-9-11(15)7-8-14(13)17(10)12-5-3-2-4-6-12/h2-9H,15H2,1H3
3018-68-6Relevant articles and documents
Novel benzimidazole-based MCH R1 antagonists
Carpenter, Andrew J.,Al-Barazanji, Kamal A.,Barvian, Kevin K.,Bishop, Michael J.,Britt, Christy S.,Cooper, Joel P.,Goetz, Aaron S.,Grizzle, Mary K.,Hertzog, Donald L.,Ignar, Diane M.,Morgan, Ronda O.,Peckham, Gregory E.,Speake, Jason D.,Swain, Will R.
, p. 4994 - 5000 (2007/10/03)
The identification of an MCH R1 antagonist screening hit led to the optimization of a class of benzimidazole-based MCH R1 antagonists. Structure-activity relationships and efforts to optimize pharmacokinetic properties are detailed along with the demonstration of the effectiveness of an MCH R1 antagonist in an animal model of obesity.
