30235-12-2 Usage
Description
2-Cyano-6-methyl-4-nitropyridine is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is characterized by the presence of a nitro group, a cyano group, and a methyl group attached to a pyridine ring, which contributes to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
2-Cyano-6-methyl-4-nitropyridine is used as a key intermediate in the synthesis of hydrochloride of 2-methyl-4-pyrrolidinyl-6-[(E)-2-(3-trifluoromethylphenyl)vinyl]pyridine, a selective Y5 receptor antagonist. This antagonist has potential applications in the treatment of various disorders related to the neuropeptide Y system, such as obesity, anxiety, and depression.
Additionally, 2-Cyano-6-methyl-4-nitropyridine can be utilized in the development of other pharmaceutical compounds with diverse therapeutic applications, owing to its versatile chemical structure and reactivity. Its presence in the synthesis process allows for the creation of new molecules with potential medicinal properties, making it a valuable component in the field of drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 30235-12-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,2,3 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 30235-12:
(7*3)+(6*0)+(5*2)+(4*3)+(3*5)+(2*1)+(1*2)=62
62 % 10 = 2
So 30235-12-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5N3O2/c1-5-2-7(10(11)12)3-6(4-8)9-5/h2-3H,1H3
30235-12-2Relevant articles and documents
OXADIAZOLE MODULATORS OF S1P METHODS OF MAKING AND USING
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Paragraph 0177, (2017/01/23)
The invention is directed to Compounds of Formula (I): wherein each variable is defined herein, as well as methods of making and using the compounds as agonists of S1P1 and/or S1P5 for instance for treating graft versus host disease and autoimmune diseases.
1,1,1-TRIFLUORO-4-PHENYL-4-METHYL-2-(1H-PYRROLO
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Page/Page column 167-168, (2010/02/11)
Compounds of Formula (IA), IB), IC), and (ID) wherein R1, R2, R3, R4, R5, and R6 are as respectively defined herein for Formula (IA), (IB), (IC), and (ID), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
Efficient synthesis of a selective Y5 receptor antagonist
Guery, Sebastien,Rival, Yveline,Wermuth, Camille G.
, p. 1715 - 1719 (2007/10/03)
A selective Y5 receptor antagonist, the hydrochloride of 2-methyl-4-pyrrolidinyl-6-[(E)-2-(3-trifluoromethylphenyl)-vinyl]pyridine, can be prepared in a 7-step synthesis.