302938-38-1

Basic information

• Product Name: 6,7-dimethoxy-3-(2-oxo-2-phenylethyl)isobenzofuran-1(3H)-one
• Synonyms: 6,7-dimethoxy-3-(2-oxo-2-phenylethyl)isobenzofuran-1(3H)-one
• CAS NO: 302938-38-1
• Molecular Weight: 312.322
• Mol File: 302938-38-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6,7-dimethoxy-3-(2-oxo-2-phenylethyl)isobenzofuran-1(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-3-(2-oxo-2-phenylethyl)isobenzofuran-1(3H)-one(302938-38-1)
• EPA Substance Registry System: 6,7-dimethoxy-3-(2-oxo-2-phenylethyl)isobenzofuran-1(3H)-one(302938-38-1)

Safety Data

• Hazardous Substances Data: 302938-38-1(Hazardous Substances Data)

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 29526-96-3 1-phenylcyclopropan-1-ol 
• 1521-38-6 2,3-dimethoxybenzoic acid 
• 519-05-1 opianic acid 
• 98-86-2 acetophenone 
• 614-20-0 3-oxo-3-phenylpropionic acid 
• 483-85-2 2-formyl-3,4-dimethoxy-benzoic acid 

Downstream Products

• 853926-36-0 6,7-dimethoxy-2-phenyl-3H-isochromeno[3,4-b]pyrrol-5-one 
• 519-05-1 opianic acid 
• 98-86-2 acetophenone 

Relevant articles and documents

Rh-Catalyzed cascade C-H activation/C-C cleavage/cyclization of carboxylic acids with cyclopropanols

Merging both C-H and C-C activation in a tandem process is a marked challenge. A novel Rh(iii)-catalyzed C-H activation/ring opening C-C cleavage/cyclization of carboxylic acids with cyclopropanols was developed for the synthesis of 3-substituted phthalides andα,β-butenolides. This reaction displays excellent functional group tolerance with respect to both carboxylic acids and cyclopropanols and features relatively mild conditions. Remarkably, the utility of this method was highlighted by the rapid construction of bioactive compounds bearing a 3-substituted phthalide frameworkvialate-stage functionalization.