3033-62-3Relevant articles and documents
Selective Synthesis of Bisdimethylamine Derivatives from Diols and an Aqueous Solution of Dimethylamine through Iridium-Catalyzed Borrowing Hydrogen Pathway
Fujita, Ken-ichi,Jeong, Jaeyoung
, (2021/12/13)
Bisdimethylamine derivatives are an important class of compounds in the polymer and pharmaceutical industries. However, existing methods for the synthesis of these compounds have several drawbacks such as low selectivity, use of toxic reagents, and generation of waste. In this study, a new system was developed for the selective synthesis of bisdimethylamine derivatives using a diol and dimethylamine as starting materials and an iridium complex bearing an N-heterocyclic carbene ligand as catalyst. The starting materials were easily available, less toxic, inexpensive, and easy to handle. The reaction proceeded efficiently through a borrowing hydrogen pathway under aqueous conditions, without any additional organic solvent, to afford various bisdimethylamine derivatives in good to excellent yields.
Production method of BDMAEE
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Paragraph 0065-0068; 0077-0111, (2019/08/01)
The invention discloses a production method of BDMAEE. The production method comprises the following steps: adding sulfuric acid, DMEA and super-strong solid acid taken as a catalyst in a reaction vessel to perform an etherification reaction; adding an extractant to obtained etherification liquid, and introducing ammonia to an extraction system to neutralize while stirring, and stopping introducing ammonia to neutralize until pH is 11-13; filtering an obtained product to achieve solid-liquid separation; washing and drying a solid obtained by filtering to obtain ammonium sulfate; and carrying out distillation on filtrate obtained by filtering to obtain BDMAEE. BDMAEE prepared by the method disclosed by the invention is high in efficiency and product yield, high in purity and less in wastewater, and can realize resource utilization of by-products.
Synthesis of bis(2-dimethylaminoethyl) ether
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Paragraph 0013, (2017/11/04)
A bis(2-dimethylaminoethyl) ether product is prepared by chlorinating 2-(2-(dimethylamino)ethoxy)ethanol, which is taken as a raw material, by using thionyl chloride to obtain a corresponding chloride; preparing the chloride and trimethylamine into quaternary ammonium salt; drying the obtained quaternary ammonium salt, then using ethylene diamine to enable one methyl of the quaternary ammonium salt to be transferred onto the ethylene diamine at high temperature, and rectifying.