30384-93-1

Basic information

• Product Name: 2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE
• Synonyms: ASINEX-REAG BAS 10156733;IFLAB-BB F2124-0673;2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE;2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE;TIMTEC-BB SBB010421;2-Methylimidazo[1,2-a]pyridine-3-carboxaldehyde 97%;2-Methyl-iMidazo[1,2-a]pyridin-3-carbaldehyde;3-Formyl-2-methyllimidazo[1,2-a]pyridine
• CAS NO: 30384-93-1
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17
• Product Categories: Aldehydes;Fused Ring Systems
• Mol File: 30384-93-1.mol
• Article Data: 12

Chemical Properties

• Melting Point: 117-118
• Appearance: /
• Density: 1.21 g/cm³
• Refractive Index: 1.622
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.24±0.10(Predicted)
• CAS DataBase Reference: 2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE(30384-93-1)
• EPA Substance Registry System: 2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE(30384-93-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 30384-93-1(Hazardous Substances Data)

Usage

General Description

2-Methyl-imidazo[1,2-a]pyridine-3-carbaldehyde is a chemical compound with a heterocyclic structure that contains an imidazole and pyridine ring. It is commonly used as a building block in the synthesis of various pharmaceuticals and agricultural chemicals. 2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE exhibits potential biological activities, including as a protein kinase inhibitor and an anti-viral agent. Its unique structure and reactivity make it a valuable tool in medicinal chemistry research for the development of new drugs. Additionally, 2-Methyl-imidazo[1,2-a]pyridine-3-carbaldehyde is also of interest in the field of organic chemistry for its role in the synthesis of complex organic molecules. Overall, this chemical compound has versatile applications in both the pharmaceutical and chemical industries.

InChI:InChI=1/C9H8N2O/c1-7-8(6-12)11-5-3-2-4-9(11)10-7/h2-6H,1H3

Upstream product

• 934-37-2 2-methylimidazo[1,2-a]pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 89021-03-4 pyridin-3-yl-)methyl>phosphonsaeure-diisopropylester 
• 63076-73-3 2-Methyl-3-(2,2,2-trichloro-1-hydroxyethyl)imidazo<1,2-a>pyridine 
• 2549-19-1 ethyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate 
• 504-29-0 2-aminopyridine 
• 1042981-20-3 2-methylimidazo[1,2-a]pyridine-5-carbaldehyde 
• 100-97-0 hexamethylenetetramine 
• 67-68-5 dimethyl sulfoxide 
• 93-61-8 N-methyl-N-phenylformamide 

Downstream Products

• 1224470-80-7 2-methyl-3-(4-phenylpiperazinylmethyl)imidazo[1,2-a]-pyridine 
• 1224470-82-9 2-methyl-3-[4-(4-chlorophenyl) piperazinylmethyl]imidazo-[1,2-a]-pyridine 
• 30489-44-2 3-(hydroxymethyl)-2-methylimidazo<1,2-a>pyridine 
• 1396397-01-5 C₁₈H₁₈N₄O₃ 
• 1396397-08-2 C₁₉H₂₀N₄O₃ 
• 29096-60-4 1-(2-methylimidazo[1,2-a]pyridin-3-yl)ethanone 

Relevant articles and documents

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A formyl Heteraromatic hydrocarbons the synthetic method of the compound of pharmaceutical intermediates

The invention relates to a method for synthesizing a formyl heterocyclic aromatic drug intermediate compound shown as a formula (I) in the specification. The method comprises the following step: enabling a compound of a formula (II) in the specification to react with a compound of a formula (III) in the specification in an organic solvent in the presence of a catalyst, an oxidant and reaction aids, thereby obtaining the compound of the formula (I), wherein R1, R2, R3 and R4 are respectively and independently selected from H, C1-C6 alkyl, C1-C6 alkoxy, phenyl or nitro. According to the method, the catalyst, oxidant, reaction aids and reaction substrate are selected and combined, so that formylation at a specific site is realized, and the method has high yield and has wide application prospects and potentials in the field of synthetic methods of drug intermediates.

Cu-Catalyzed selective C3-formylation of imidazo[1,2-a]pyridine C-H bonds with DMSO using molecular oxygen

Using the widely available DMSO as the formylation reagent under oxidative conditions, an efficient Cu-catalyzed C3-formylation reaction of imidazo[1,2-a]pyridine C-H bonds to directly generate structurally sophisticated 3-formyl imidazo[1,2-a]pyridine derivatives has been developed. The reaction proceeded to generate products in good yields, and used the environmentally friendly molecular oxygen as the oxidant.