305837-95-0

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-(3-phenyl-2-propynyl)-
• CAS NO: 305837-95-0
• Molecular Formula: C16H15NO2S
• Molecular Weight: 285.367
• Mol File: 305837-95-0.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 451.0±55.0 °C(Predicted)
• Density: 1.26±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-(3-phenyl-2-propynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-(3-phenyl-2-propynyl)-(305837-95-0)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-(3-phenyl-2-propynyl)-(305837-95-0)

Safety Data

• Hazardous Substances Data: 305837-95-0(Hazardous Substances Data)

Upstream product

• 78168-74-8 3-phenyl-prop-2-ynylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 30011-36-0 3-phenylprop-2-yn-1-amine hydrochloride 
• 591-50-4 iodobenzene 
• 2450-71-7 Propargylamine 
• 55022-46-3 4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 70-55-3 toluene-4-sulfonamide 
• 189031-66-1 N-(tert-butoxycarbonyl)-4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 81005-27-8 (N-(2,2-dimethyl-propionyl)-4-methyl-benzenesulfonamide) 
• 189031-59-2 N-tert-butoxylcarbonyl-N-(3-phenylprop-2-ynyl)-(4-toluene)sulfonamide 
• 82490-61-7 3-phenyl-2-propyn-1-yl methanesulfonate 

Downstream Products

• 5848-57-7 N-<3-phenyl-2(Z)-propenyl>-4-methylphenylsulfonamide 
• 1451188-06-9 N-[2-(4-methoxyphenyl)prop-2-en-1-yl]-4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide 
• 1451188-09-2 N-[2-(1H-indol-5-yl)prop-2-en-1-yl]-4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide 
• 1451188-13-8 4-methyl-N-(3-phenylprop-2-yn-1-yl)-N-[2-(pyridine-3-yl)prop-2-en-1-yl]benzenesulfonamide 
• 1451188-10-5 4-methyl-N-(3-phenylprop-2-yn-1-yl)-N-[2-(thienyl)prop-2-en-1-yl]benzenesulfonamide 
• 1451188-04-7 4-methyl-N-[2-(4-methylphenyl)prop-2-en-1-yl]-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide 
• 1451188-05-8 N-[2-(4-chlorophenyl)prop-2-en-1-yl]-4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide 
• 1451188-08-1 4-methyl-N-(3-phenylprop-2-yn-1-yl)-N-{2-[4-(trifluoromethyl)phenyl]prop-2-en-1-yl}benzenesulfonamide 
• 1451188-21-8 1-(4-methylphenyl)-3-[(4-methylphenyl)sulfonyl]-6-phenyl-3-azabicyclo[4.1.0]hept-4-ene 
• 1451188-22-9 1-(4-chlorophenyl)-3-[(4-methylphenyl)sulfonyl]-6-phenyl-3-azabicyclo[4.1.0]hept-4-ene 
• 1451188-23-0 1-(4-methoxyphenyl)-3-[(4-methylphenyl)sulfonyl]-6-phenyl-3-azabicyclo[4.1.0]hept-4-en 
• 1451188-25-2 3-[(4-methylphenyl)sulfonyl]-6-phenyl-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[4.1.0]hept-4-ene 
• 1451188-26-3 5-{3-[(4-methylphenyl)sulfonyl]-6-phenyl-3-azabicyclo[4.1.0]hept-4-en-1-yl}-1H-indole 
• 1451188-27-4 3-[(4-methylphenyl)sulfonyl]-6-phenyl-1-(2-thienyl)-3-azabicyclo[4.1.0]hept-4-ene 

Relevant articles and documents

Nickel-catalyzed asymmetric arylative cyclization of N-alkynones: Efficient access to 1,2,3,6-tetrahydropyridines with a tertiary alcohol

Nickel/(S)-t-Bu-PHOX complex catalyzed asymmetric arylative cyclization of N-alkynones has been achieved, delivering 1,2,3,6-tetrahydropyridines containing a chiral tertiary alcohol in high yields and excellent enantioselectivities, which provides efficient access to chiral tetrahydropyridine and piperidine analogues.

Enantioselective Nickel-Catalyzed anti-Arylmetallative Cyclizations onto Acyclic Ketones

Domino reactions involving nickel-catalyzed additions of (hetero)arylboronic acids to alkynes, followed by cyclization of the alkenylnickel intermediates onto tethered acyclic ketones to give chiral tertiary-alcohol-containing products in high enantioselectivities, are described. The reversible E/Z isomerization of the alkenylnickel intermediates enables overall anti-arylmetallative cyclization to occur. The ring system of the products are substructures of certain diarylindolizidine alkaloids.

Cu(I)-catalyzed oxidative cyclization of enynamides: Regioselective access to cyclopentadiene frameworks and 2-aminofurans

An efficient Cu(I)-catalyzed oxidative cyclization of alkynyl-tethered enynamides for the construction of fused bicyclic cyclopentadiene derivatives is disclosed. The cascade proceeds through alkyne oxidation, carbene/alkyne metathesis, and formal (3 + 2)