306960-30-5Relevant articles and documents
Pyridopyrimidinones
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, (2008/06/13)
The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X′ have the designations cited in patent claim 1. Said c
SULFONAMIDES
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, (2008/06/13)
The invention relates to compounds of formula (I) in which R6, R7, R8, R9 and X have the meanings cited in Claim 1. These compounds are inhibitors of tyrosinkinases, particularly TIE-2, and Raf kinases and can, among other things, be used for treating tumors.
Pyrido[2,3-d]pyrimidine and pyrimido[4,5-d]pyrimidine nucleosides
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, (2008/06/13)
A purine nucleoside analog includes a pyrido[2,3-d]pyrimidine or a pyrimido[4,5-d]pyrimidine and further has a sugar moiety that is optionally modified at the C2′, C3′, C4′ and/or C5′ position. Particularly contemplated compounds also include prodrug forms of the purine nucleoside analogs, and both purine nucleoside analogs and the corresponding prodrugs are employed in the reduction of growth of neoplastic cells.