30779-85-2

Basic information

• Product Name: 3-benzyl-4H-chromen-4-one
• Synonyms: 4H-1-benzopyran-4-one, 3-(phenylmethyl)-
• CAS NO: 30779-85-2
• Molecular Formula: C₁₆H₁₂O₂
• Molecular Weight: 236.2653
• Mol File: 30779-85-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 377.2°C at 760 mmHg
• Flash Point: 171.8°C
• Density: 1.221g/cm³
• Vapor Pressure: 6.85E-06mmHg at 25°C
• Refractive Index: 1.631
• CAS DataBase Reference: 3-benzyl-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-4H-chromen-4-one(30779-85-2)
• EPA Substance Registry System: 3-benzyl-4H-chromen-4-one(30779-85-2)

Safety Data

• Hazardous Substances Data: 30779-85-2(Hazardous Substances Data)

Upstream product

• 3516-95-8 2'-hydroxy-3-phenylpropiophenone 
• 109-94-4 formic acid ethyl ester 
• 30779-90-9 (E)-3-benzylidenechroman-4-one 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 50684-40-7 3-benzyl-4-chromanone 
• 1776-08-5 (E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one 
• 100-39-0 benzyl bromide 
• 124-63-0 methanesulfonyl chloride 
• 118-93-4 o-hydroxyacetophenone 
• 100-52-7 benzaldehyde 

Downstream Products

• 4198-01-0 3-(α-Hydroxybenzoyl)chromone 
• 99217-74-0 3-benzylchroman 

Relevant articles and documents

Synthesis and biological activity of (±)-7,3′,4′-trihydroxyhomoisoflavan and its analogs

Acetylcholinesterase (AChE) inhibitors and neurite outgrowth promoters are thought to alleviate the symptoms of degenerative brain disorders, such as Alzheimer's disease. We designed and synthesized a series of homoisoflavonoids based on the structure of natural homoisoflavan isolated from Dracaena cambodiana dragon's blood. The homoisoflavonoids were then evaluated as AChE inhibitors and neurite outgrowth promoters. The catechol structure of the homoisoflavan B rings was important for AChE inhibition, and some of the homoisoflavonoids significantly promoted neurite outgrowth induced by nerve growth factor (NGF).

Synthesis of 3-allylchromones, homoisoflavones and bischromones from (E)-1-(2-Hydroxyphenyl)-3-(N,N-dimethylamino)prop-2-en-1-one

(E)-1-(2-Hydroxyphenyl)-3-(N,N-dimethylamino)prop-2-en-1-one reacts with allyl bromide, prenyl bromide, benzyl bromide and α,α'-dibromo-p- xylene in DMF to produce 3-allyl-, 3-prenyl-chromones, homoisoflavones and bischromones, respectively. Similar compo

Reactivity of α-arylidene benzoheteracyclanone dibromides toward azide ion: An effective approach to 3-(α-substituted-benzyl)chromones and -1-thiochromones

Treatment of dibromides of 3-arylidenechromanones and -1-thiochromanones with sodium azide resulted in the formation of 3-(α-azidobenzyl)chromones and -1-thiochromones whereas dibromides having no antiperiplanar vicinal hydrogen in the ring such as flavanone, 1-thioflavanone and benzosuberone derivatives afforded only the parent enones by bromine elimination. Evidence supported the intermediacy of 3-(α-bromobenzyl)chromones and -1-thiochromones in this reaction. These postulated intermediates were prepared in an independent way and transformed into azides in high yield.