3098-67-7

Basic information

• Product Name: 1,3-DIACETYL-4,6-DIMETHOXYBENZENE
• Synonyms: Benzene,1,5-diacetyl-2,4-dimethoxy- (6CI,7CI,8CI); 1,5-Diacetyl-2,4-dimethoxybenzene;4,6-Diacetylresorcinol dimethyl ether
• CAS NO: 3098-67-7
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.24
• Mol File: 3098-67-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 373.9°Cat760mmHg
• Flash Point: 167°C
• Appearance: /
• Density: 1.108g/cm³
• CAS DataBase Reference: 1,3-DIACETYL-4,6-DIMETHOXYBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DIACETYL-4,6-DIMETHOXYBENZENE(3098-67-7)
• EPA Substance Registry System: 1,3-DIACETYL-4,6-DIMETHOXYBENZENE(3098-67-7)

Safety Data

• Hazardous Substances Data: 3098-67-7(Hazardous Substances Data)

Usage

General Description

1,3-Diacetyl-4,6-dimethoxybenzene is a chemical compound with the molecular formula C10H12O4. It is a derivative of benzene with two acetyl groups and two methoxy groups attached to it. 1,3-DIACETYL-4,6-DIMETHOXYBENZENE is commonly used as a flavoring agent in the food industry, providing a sweet and fruity aroma to various products. It is also used in fragrances and perfumes for its pleasant scent. However,

Upstream product

• 2161-85-5 1-(5-acetyl-2,4-dihydroxyphenyl)-1-ethanone 
• 77-78-1 dimethyl sulfate 
• 75-36-5 acetyl chloride 
• 151-10-0 1,3-Dimethoxybenzene 
• 7446-70-0 aluminium trichloride 
• 91143-38-3 1-(4-acetoxy-2-methoxy-phenyl)-ethanone 
• 98-95-3 nitrobenzene 
• 108-46-3 recorcinol 
• 74-88-4 methyl iodide 

Downstream Products

• 856084-84-9 1,5-dimethoxy-2,4-bis-(3-oxo-3-phenyl-propionyl)-benzene 
• 100118-60-3 1,5-diacetoxy-2,4-dimethoxy-benzene 
• 2161-85-5 1-(5-acetyl-2,4-dihydroxyphenyl)-1-ethanone 
• 52959-34-9 2,4-diethyl-1,5-dimethoxybenzene 
• 7168-99-2 4,6-dimethoxy-isophthalic acid 
• 117690-94-5 4-(4-cyanobutoxy)-5-acetyl-2-hydroxy-acetophenone 
• 861606-45-3 1-{2,4-dimethoxy-5-[3-(3,4-dimethoxyphenyl)-2-propenoyl]phenyl}-3-(3,4-dimethoxyphenyl)-2-propen-1-one 

Relevant articles and documents

Microwave-assisted synthesis of bis(N-substituted thiazol-2-amine) derivatives and their biological activities

New 4,4′-(4,6-dimethoxy-1,3-phenylene)-bis(N-substituted thiazol-2-amine) derivatives 5a-j were synthesized from 1,1′-(4,6-dimethoxy-1,3-phenylene)-bis(2-bromoethanone) 3 and substituted thioureas 4a-j under conventional and microwave irradiation conditio

Microwave assisted synthesis of some novel bis-(2-substituted imidazole[2,1-b] [1,3,4] thiadiazole) derivatives and their biological activities

A new series of 6,6'-(4,6-dimethoxy-1,3-phenylene)bis (2- substituted imidazo[2,1-b] [1,3,4]thiadiazole) derivatives (5a-5h) were synthesized from corresponding 1,1'-(4,6-dimethoxy-1,3-phenylene)bis(2-bromoethanone) and substituted 1,3,4-thiadiazol-2-amine under conventional and microwave irradiation conditions. The structures of all the synthesized compounds were characterized by Fourier transform infrared,1H nuclear magnetic resonance (NMR),13C NMR, mass, and elemental analysis. All products were subjected to in vitro antibacterial and antimycobacterial evaluation. Some of the compounds exhibit good activities against Staphylococcus aureus (+ve), Bacillus subtilis (+ve) strains, and Mycobacterium bovis strain.

Leukotriene B4 Receptor Antagonists: The LY255283 Series of Hydroxyacetophenones

A series of hydroxyacetophenones was prepared for evaluation as leukotriene B4 (LTB4) receptor antagonists, culminating in 1-oxy>phenyl>ethanone (compound 35, LY255283).Using an assay for inhibition of specific LTB4 binding to human PMN, we found that substitution of a nonpolar substituent in the 5-position was required for activity.Best activity was realized with hydrogen in the 3-position, hydroxyl in the 2-position, short chain alkyl ketone in the 1-position, and a six- or eight-carbon chain linking the oxygen in the 4-position with an unsaturated terminal function.Compound 35, having an IC50 of 87 nM in the binding assay, was chosen for further preclinical evaluation.