3099-82-9

Basic information

• Product Name: Diazene, chlorophenyl-
• CAS NO: 3099-82-9
• Molecular Formula: C6H5ClN2
• Molecular Weight: 140.572
• Mol File: 3099-82-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Diazene, chlorophenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Diazene, chlorophenyl-(3099-82-9)
• EPA Substance Registry System: Diazene, chlorophenyl-(3099-82-9)

Safety Data

• Hazardous Substances Data: 3099-82-9(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 

Downstream Products

• 119701-67-6 2,3-dihydro-2-imino-3-phenyl-5-thienoyl-1,3,4-thiadiazole 
• 29679-09-2 2-Nitro-2-phenylazo-propionanilid 
• 29679-10-5 2-Cyano-2-phenylazo-propionamid 
• 20271-37-8 ethyl 5-amino-1-phenyl-1,2,3-triazole-4-carboxylate 
• 40697-35-6 2-phenylhydrazono-propionitrile 
• 111680-58-1 4-Amino-5-cyano-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid 
• 24793-45-1 3-amino-4-phenylazo-2-isoxazolin-5-one 
• 74676-86-1 5-amino-3-hydroxy-4-phenylazoisoxazole 
• 107836-27-1 3-Oxo-2,5-diphenyl-6-phenylazo-2,3-dihydro-pyridazine-4-carbonitrile 
• 107836-25-9 C₂₃H₁₆N₆ 
• 107836-31-7 3-Imino-2,5-diphenyl-2,3-dihydro-pyridazine-4-carbonitrile 
• 107836-33-9 3-Imino-5-methyl-2-phenyl-2,3-dihydro-pyridazine-4-carbonitrile 
• 89516-24-5 ethyl 5-cyano-4-methyl-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate 
• 174906-51-5 3-(5-Imino-4-phenyl-4,5-dihydro-[1,3,4]thiadiazole-2-carbonyl)-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile 

Relevant articles and documents

Ketohydrazone dyes derived from 4-morpholino-2-naphthol and ortho-substituted anilines: Further examination of the hyperchromism induced by the 4-morpholino-2-naphthol moiety

A series of ketohydrazone dyes has been synthesised from 4-morpholino-2-naphthol and ortho-substituted anilines by conventional diazotisation coupling chemistry. Whilst the new, dull orange-red, dyes exhibit only a minor variation of absorption maxima acr

Synthesis and structure-activity relationships of 6-heterocyclic- substituted purines as inactivation modifiers of cardiac sodium channels

Purine-based analogs of SDZ 211-500 (5) were prepared and evaluated as inactivation modifiers of guinea pig or human cardiac sodium (Na) channels expressed in Xenopus oocytes. Substances which remove or slow the Na channel inactivation process in cardiac tissue are anticipated to prolong the effective refractory period and increase inotropy and thus have potential utility as antiarrhythmic agents. Heterocyclic substitution at the 6-position of the purine ring resulted in compounds with increased Na activity and potency, with 5-membered heterocycles being optimal. Only minor modifications to the benzhydrylpiperazine side chain were tolerated. Selected compounds which delayed the inactivation of Na channels were found to increase refractoriness and contractility in a rabbit Langendorff heart model, consistent with the cellular mechanism. Activity in both the oocyte and rabbit heart assays was specific to the S enantiomers. Preliminary in vivo activity has been demonstrated following intravenous infusion. The most promising compound on the basis of in vitro data is the formylpyrrole (S)74, which is 25-fold more potent than DPI 201-106 (1) in the human heart Na channel assay.