311312-20-6

Basic information

• Product Name: Silanol, dimethyl(1-methylene-4-phenylbutyl)-
• CAS NO: 311312-20-6
• Molecular Formula: C13H20OSi
• Molecular Weight: 220.387
• Mol File: 311312-20-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Silanol, dimethyl(1-methylene-4-phenylbutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silanol, dimethyl(1-methylene-4-phenylbutyl)-(311312-20-6)
• EPA Substance Registry System: Silanol, dimethyl(1-methylene-4-phenylbutyl)-(311312-20-6)

Safety Data

• Hazardous Substances Data: 311312-20-6(Hazardous Substances Data)

Upstream product

• 541-05-9 Hexamethylcyclotrisiloxane 

Downstream Products

• 97455-11-3 (E)-β-(3-phenyl-1-propyl)styrene 
• 103682-35-5 pent-4-ene-1,4-diyldibenzene 
• 1075-74-7 5-phenylpent-1-ene 

Relevant articles and documents

Vinyldimethylphenylsilanes as safety catch silanols in fluoride-free palladium-catalyzed cross-coupling reactions

A series of five structurally diverse vinyldimethylphenylsilanes have been shown to undergo a fluoride-free one-pot palladium-catalyzed cross-coupling reaction with phenyl iodide to give ipso coupled products in 62-86% yield. The limitations of this present protocol lie in the activation of Si-Ph vs protodesilylation by KOTMS/18-C-6, which seems sensitive to the sterics of cis substituents, but not geminal substituents.

Strategies for protodesilylation of C-2 trialkylsilyl terminal alkenes

The mild and high yielding protodesilylation of C-2 trialkylsilyl terminal alkenes can be effected via a hydroboration-Peterson elimination protocol or, in the case of the phenyldimethylsilyl analogues, a one pot procedure using t-BuOK-18-C-6-TBAF can be used. The Royal Society of Chemistry 2000.