312329-87-6

Basic information

• Product Name: Benzenesulfonamide, N-ethynyl-4-methyl-N-phenyl-
• CAS NO: 312329-87-6
• Molecular Formula: C15H13NO2S
• Molecular Weight: 271.34
• Mol File: 312329-87-6.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-ethynyl-4-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-ethynyl-4-methyl-N-phenyl-(312329-87-6)
• EPA Substance Registry System: Benzenesulfonamide, N-ethynyl-4-methyl-N-phenyl-(312329-87-6)

Safety Data

• Hazardous Substances Data: 312329-87-6(Hazardous Substances Data)

Upstream product

• 1198340-49-6 (E)-N-(1,2-dichlorovinyl)-4-methyl-N-phenylbenzenesulfonamide 
• 68-34-8 phenyl toluenesulfonamide 
• 74-86-2 acetylene 
• 1252671-79-6 1-ethynyl-1,2-benziodoxol-3(1H)-one 
• 125803-61-4 ethynylphenyl-iodonium-1,1,1-trifluoromethanesulfonate 
• 75-35-4 1,1-Dichloroethylene 
• 1092383-27-1 4-methyl-N-phenyl-N-[2-[tris(1-methylethyl)silyl]-ethynyl]-benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 62-53-3 aniline 
• 68984-88-3 N-Formyl-N-phenyl-4-methyl-benzenesulfonamide 
• 75-03-6 ethyl iodide 
• 312329-83-2 N-(2,2-dichlorovinyl)-N-phenyl-4-methyl-benzenesulfonamide 
• 74-88-4 methyl iodide 

Downstream Products

• 676591-83-6 4-methyl-N-phenyl-N-[(trimethylsilyl)ethynyl]benzenesulfonamide 
• 1403981-68-9 (E)-2-(2-(benzylideneamino)phenyl)-N-phenyl-N-tosylacetamide 

Relevant articles and documents

Synthesis of cis-β-Amidevinyl Benziodoxolones from the Ethynyl Benziodoxolone-Chloroform Complex and Sulfonamides

The synthesis of cis-β-amidevinyl benziodoxolones from the ethynyl benziodoxolone-chloroform complex and sulfonamides is reported. Evidence indicates that highly reactive unsubstituted ethynyl benziodoxolone undergoes Michael addition of sulfonamides, including sterically demanding acyclic amino acid derivatives. The synthesis of selectively deuterated cis-β-amidevinyl benziodoxolones and investigation of ethynyl-λ3-iodane reactivity are also described.

Photo-induced synthesis of β-sulfonyl imides from carboxylic acids

A photo-induced imidation process of carboxylic acids is described. Numerous carboxylic acids could convert to β-sulfonyl imides in the presence ofN-sulfonyl ynamides under visible light irradiation. Control experiments and mechanistic studies demonstrate that this imidation process involves a hydroacyloxylation/radical rearrangement cascade. This protocol represents a direct imidation method from carboxylic acids under mild conditions, with broad scope and high atom-economy.

MANUFACTURING METHOD OF CRYSTAL ETHYNYL GROUP SUBSTITUTED HYPERVALENT IODINE COMPOUND, AND INTRODUCTION METHOD OF ETHYNYL GROUP INTO AMINO GROUP USING THE SAME

PROBLEM TO BE SOLVED: To provide an effective introduction method of an ethynyl group in fields of organic synthesis and chemical biology by stabilizing ethynyl benziodoxolone which is highly thermally unstable. SOLUTION: The above described problem is solved by isolating as a crystal ethynyl benziodoxolone complex stabilized by taking a solvent X into ethynyl benziodoxolone and letting n X represented by the following formula (1) coordinate and using the same in a reaction for introducing an ethynyl group. R1 is hydrogen, an alkyl group having a linear or branched structure constituted by C1 to C5 carbon atom, a chloro group, a bromo group, a fluoro group, a nitro group, and a cyano group, X is acetonitrile, chloroform, ethyl acetate, water, n is molecular number of a solvent represented by any integer or fraction, and a crystal composition is formed by being taken into a crystal ethynyl substituted hypervalent iodine. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT