312760-15-9

Basic information

• Product Name: 2-benzenesulfonylamino-3-({5-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-thiophene-2-carbonyl}-amino)-propionic acid tert-butyl ester
• Synonyms: 2-benzenesulfonylamino-3-({5-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-thiophene-2-carbonyl}-amino)-propionic acid tert-butyl ester
• CAS NO: 312760-15-9
• Molecular Weight: 615.772
• Mol File: 312760-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzenesulfonylamino-3-({5-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-thiophene-2-carbonyl}-amino)-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzenesulfonylamino-3-({5-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-thiophene-2-carbonyl}-amino)-propionic acid tert-butyl ester(312760-15-9)
• EPA Substance Registry System: 2-benzenesulfonylamino-3-({5-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-thiophene-2-carbonyl}-amino)-propionic acid tert-butyl ester(312760-15-9)

Safety Data

• Hazardous Substances Data: 312760-15-9(Hazardous Substances Data)

Upstream product

• 68819-84-1 tert-butyl N-(4-bromobenzyl)carbamate 

Downstream Products

• 312760-16-0 C₃₆H₄₇N₅O₉S₂ 
• 603127-91-9 3-{[5-(4-aminomethyl-phenyl)-thiophene-2-carbonyl]-amino}-2-benzenesulfonylamino-propionic acid tert-butyl ester 

Relevant articles and documents

Thiophene-based vitronectin receptor antagonists

A series of αvβ3 antagonists based on a thiophene scaffold were synthesized via two routes and evaluated for in vitro biological activity. We have identified several structurally similar antagonists with different selectivities towards αIIbβ3, αvβ5 and α5β1 at the cellular level. In addition, these antagonists exerted an antiangiogenic effect in the chick chorioallantoic membrane (CAM) assay.